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MedXY AI/MedXY News/Tag: Neutropenia
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Impact of Clonal Hematopoiesis and Pre-treatment Neutropenia on CAR-T Cell Therapy Outcomes in Hematological Malignancies
Hematology-OncologyCAR-T TherapyClonal hematopoiesis

Impact of Clonal Hematopoiesis and Pre-treatment Neutropenia on CAR-T Cell Therapy Outcomes in Hematological Malignancies

By MedXY|Oct 9, 2026

This study evaluates how clonal hematopoiesis of indeterminate potential (CHIP) and pre-treatment neutropenia affect clinical outcomes and toxicities in patients undergoing CAR-T therapy for hematologic cancers, revealing nuanced risks for

Methimazole-Associated Neutropenia Common in Pediatric Graves Disease: Chinese Cohort Study
Diabetes & EndocrinologyGraves diseasemethimazole

Methimazole-Associated Neutropenia Common in Pediatric Graves Disease: Chinese Cohort Study

By MedXY|Jul 26, 2026

A cohort of 432 children with Graves disease found 24% developed neutropenia on methimazole, mostly within the first month. TPOAb-negative status and younger age increased risk.

Peg-GCSF Primary Prophylaxis Effectively Mitigates Severe Neutropenia and Enhances Quality of Life in mFOLFIRINOX-Treated Pancreatic Cancer
GastroenterologymFOLFIRINOXNeutropenia

Peg-GCSF Primary Prophylaxis Effectively Mitigates Severe Neutropenia and Enhances Quality of Life in mFOLFIRINOX-Treated Pancreatic Cancer

By MedXY|Dec 29, 2025

A randomized phase 2 trial demonstrates that primary prophylaxis with peg-GCSF significantly reduces grade 3-4 and febrile neutropenia in patients with unresectable pancreatic cancer receiving mFOLFIRINOX, while improving patient-reported q

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