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MedXY News - Mortality

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Lean MASLD Is Not Benign: Higher Liver Events and Mortality in Normal-BMI Patients Across Three Large Cohorts

Lean MASLD Is Not Benign: Higher Liver Events and Mortality in Normal-BMI Patients Across Three Large Cohorts

A pooled analysis of three population cohorts shows lean MASLD carries higher risks of liver-related events and all-cause and liver-related mortality despite lower cardiovascular event risk compared with non-lean MASLD.

Section: GastroenterologyNov 7, 2025

Postoperative Vasopressor Use After Noncardiac Surgery: Patterns, Outcomes, and Clinical Implications from a Global Observational Study

Postoperative Vasopressor Use After Noncardiac Surgery: Patterns, Outcomes, and Clinical Implications from a Global Observational Study

An international study reveals that postoperative vasopressor infusions after noncardiac surgery vary widely across hospitals and are linked to higher mortality and complications, highlighting the need for optimized management strategies.

Section: AnesthesiologyOct 27, 2025

Warm and Cold Risks: How Temperature Variations Impact Mortality in Swedish Heart Failure Patients

Warm and Cold Risks: How Temperature Variations Impact Mortality in Swedish Heart Failure Patients

This study reveals that both low and high ambient temperatures significantly increase mortality risk among Swedish heart failure patients, highlighting the need for climate adaptation strategies in high-latitude regions.

Section: CardiologyOct 25, 2025

Early Adolescent Mental Well-Being as a Predictor of Long-Term Health Outcomes

Early Adolescent Mental Well-Being as a Predictor of Long-Term Health Outcomes

This study highlights how poor mental well-being during adolescence predicts increased risks of mental illness, risky behaviors, and mortality in young adulthood, emphasizing the urgency for early identification and intervention.

Section: PsychiatryOct 19, 2025

Comparative Effectiveness of Long-Acting Injectable Versus Oral Antipsychotics in Older Adults with Schizophrenia: Insights from Hong Kong’s Population-Based Study

Comparative Effectiveness of Long-Acting Injectable Versus Oral Antipsychotics in Older Adults with Schizophrenia: Insights from Hong Kong’s Population-Based Study

This study compares long-acting injectable to oral antipsychotics in older schizophrenia patients, highlighting benefits in relapse prevention and mortality reduction, with specific considerations for adverse effects.

Section: Internal MedicineOct 19, 2025

Persistent High Mortality in Severe Alcohol-Associated Hepatitis: Insights from a Five-Decade Meta-Analysis

Persistent High Mortality in Severe Alcohol-Associated Hepatitis: Insights from a Five-Decade Meta-Analysis

This meta-analysis reveals that short-term mortality in severe alcohol-associated hepatitis remains high, with no significant improvement over the past four decades despite advances in care, underscoring the urgent need for better therapies

Section: GastroenterologyOct 9, 2025

Endothelial Glycocalyx Degradation in Sepsis: Insights from the CLOVERS Trial on Fluid Resuscitation Strategies and Mortality

Endothelial Glycocalyx Degradation in Sepsis: Insights from the CLOVERS Trial on Fluid Resuscitation Strategies and Mortality

This article reviews findings from the CLOVERS trial analyzing endothelial glycocalyx degradation in sepsis, demonstrating its strong association with mortality but showing no impact of liberal versus restrictive fluid resuscitation strateg

Section: Clinical UpdatesOct 8, 2025

Mediterranean Diet Outperforms Other Dietary Patterns in Reducing Mortality via Inflammatory Pathways: Insights from a Causal Inference Analysis

Mediterranean Diet Outperforms Other Dietary Patterns in Reducing Mortality via Inflammatory Pathways: Insights from a Causal Inference Analysis

A causal analysis of nine dietary patterns reveals the Mediterranean diet as most effective in reducing all-cause and cardiovascular mortality, primarily through modulation of inflammatory biomarkers such as CRP, NPR, and SII.

Section: Clinical UpdatesOct 8, 2025

Hospital Addiction Consult Services: A Promising Step to Reduce Emergency Visits Among Patients with Opioid Use Disorder

Hospital Addiction Consult Services: A Promising Step to Reduce Emergency Visits Among Patients with Opioid Use Disorder

A hospital-based addiction consult program lowered emergency department visits in opioid use disorder patients but did not reduce hospitalizations or mortality, highlighting the need for comprehensive care beyond hospital walls.

Section: newsOct 8, 2025

Kidney Tubular Biomarkers as Predictors of Mortality and Heart Failure Readmission in Acute Heart Failure Patients

Kidney Tubular Biomarkers as Predictors of Mortality and Heart Failure Readmission in Acute Heart Failure Patients

Kidney tubular damage biomarkers independently predict death and heart failure readmission in acute heart failure, highlighting novel risk stratification beyond traditional glomerular measures.

Section: CardiologyOct 7, 2025

Anti-Inflammatory Diet and Alzheimer’s Disease Mortality: Insights from a National Cohort Study

Anti-Inflammatory Diet and Alzheimer’s Disease Mortality: Insights from a National Cohort Study

Higher adherence to an anti-inflammatory diet is linked to lower all-cause mortality and a trend toward reduced Alzheimer’s disease mortality, particularly among men and non-Hispanic Whites, highlighting dietary modification as a potential

Section: Family Medicine & NutritionOct 7, 2025

Surgical Management of Left-Sided Infective Endocarditis: Insights from the Nationwide NIDUS Registry

Surgical Management of Left-Sided Infective Endocarditis: Insights from the Nationwide NIDUS Registry

A nationwide Danish study reveals that while 40% of left-sided infective endocarditis patients have surgical indications, only half undergo surgery. Those receiving surgery are younger, less comorbid, and show improved survival, underscorin

Section: CardiologyOct 7, 2025

How Much Exercise is Too Much? Unveiling the Goldilocks Zone of Physical Activity for Healthy Aging

How Much Exercise is Too Much? Unveiling the Goldilocks Zone of Physical Activity for Healthy Aging

Recent research reveals a U-shaped relationship between exercise and biological aging, showing that moderate exercise slows aging best, while inactivity or excessive exercise may accelerate it.

Section: Family Medicine & NutritionOct 7, 2025

Global Shifts in Pulmonary Embolism Mortality: A 2001-2023 WHO Database Analysis

Global Shifts in Pulmonary Embolism Mortality: A 2001-2023 WHO Database Analysis

Analysis of WHO data reveals declining global pulmonary embolism mortality overall, with marked differences by region and income, highlighting urgent needs in lower-middle-income countries.

Section: Critical CareOct 5, 2025

Higher Calorie Intake Plus Adequate Exercise Linked to Lower Mortality Compared to Low-Calorie Diet with Exercise: Insights from NHANES Data

Higher Calorie Intake Plus Adequate Exercise Linked to Lower Mortality Compared to Low-Calorie Diet with Exercise: Insights from NHANES Data

An observational study from NHANES reveals that higher calorie intake combined with adequate exercise reduces all-cause and cardiovascular mortality more than a low-calorie diet with similar exercise levels.

Section: Clinical UpdatesOct 5, 2025

Dynamic Triglyceride-Glucose Index Trajectories as Predictors of Mortality in Critically Ill Patients with Atrial Fibrillation

Dynamic Triglyceride-Glucose Index Trajectories as Predictors of Mortality in Critically Ill Patients with Atrial Fibrillation

A retrospective study shows high and fluctuating triglyceride-glucose (TyG) index trajectories predict increased short- and long-term mortality in ICU patients with atrial fibrillation, highlighting TyG dynamics as a valuable prognostic bio

Section: CardiologyOct 5, 2025

Dynamic Triglyceride-Glucose Index Trajectories Predict Mortality in Critically Ill Atrial Fibrillation Patients

Dynamic Triglyceride-Glucose Index Trajectories Predict Mortality in Critically Ill Atrial Fibrillation Patients

This study reveals that fluctuating high triglyceride-glucose (TyG) index trajectories in critically ill atrial fibrillation patients significantly predict increased all-cause mortality up to one year post-ICU admission, offering a novel pr

Section: CardiologyOct 5, 2025

Global Impact of Cardiovascular Risk Factors on Lifetime Cardiovascular Disease Burden and Mortality: A Comprehensive Evidence Synthesis

Global Impact of Cardiovascular Risk Factors on Lifetime Cardiovascular Disease Burden and Mortality: A Comprehensive Evidence Synthesis

This review integrates data from over two million individuals globally, showing that absence of five key cardiovascular risk factors at age 50 confers a life expectancy advantage exceeding a decade, with midlife modification of hypertension

Section: CardiologyOct 5, 2025

Hypervitaminosis B12 and Mortality Risk: Unraveling the Controversy Through a Global Systematic Review and Meta-Analysis

Hypervitaminosis B12 and Mortality Risk: Unraveling the Controversy Through a Global Systematic Review and Meta-Analysis

A comprehensive meta-analysis reveals that elevated serum vitamin B12 levels do not conclusively predict increased all-cause mortality risk in adults, highlighting the complexity and heterogeneity of existing research.

Section: Family Medicine & NutritionOct 4, 2025

Delirium in Acute General Medicine: A Decade-Long Study on Occurrence, Risk Factors, and Long-Term Outcomes

Delirium in Acute General Medicine: A Decade-Long Study on Occurrence, Risk Factors, and Long-Term Outcomes

This 10-year study from England details delirium’s prevalence, associated factors like dementia and frailty, and its lasting impact on mortality and care needs in acute general medicine patients, supporting targeted screening and interventi

Section: Clinical UpdatesOct 3, 2025

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