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Assessing Early Pregnancy Exposure to Anti-CGRP Monoclonal Antibodies and Propranolol: Implications for Spontaneous Abortion Risk
NeurologyMigrainePregnancy

Assessing Early Pregnancy Exposure to Anti-CGRP Monoclonal Antibodies and Propranolol: Implications for Spontaneous Abortion Risk

By MedXY|Oct 19, 2026

This study evaluates the association between early pregnancy use of anti-CGRP monoclonal antibodies or propranolol and spontaneous abortion risk, finding increased risk with anti-CGRP mAbs but not with propranolol.

Earlier Intervention with Migraine Trigger-Site Surgery Linked to Improved Postoperative Headache Outcomes: Insights from a Taiwanese Cohort Study
Neurology
headache frequency
Migraine

Earlier Intervention with Migraine Trigger-Site Surgery Linked to Improved Postoperative Headache Outcomes: Insights from a Taiwanese Cohort Study

By MedXY|Oct 2, 2026

A retrospective cohort study reveals that shorter duration from migraine onset to trigger-site surgery predicts better postoperative headache frequency reduction, underscoring the benefit of early surgical intervention in medically refracto

Frequency of Migraine and Sinus Headaches in Patients Undergoing Primary Rhinoplasty: A Clinical Review
Clinical UpdatesRhinoplastyMigraine

Frequency of Migraine and Sinus Headaches in Patients Undergoing Primary Rhinoplasty: A Clinical Review

By MedXY|Aug 7, 2026

This review analyzes the increased incidence of migraine and sinus headaches in primary rhinoplasty patients, emphasizing the clinical significance of screening rhinogenic headache triggers during septorhinoplasty to enhance both symptomati

Atogepant Shows Better Tolerability and Efficacy Than Topiramate in Migraine Prevention: TEMPLE Trial Results
NeurologyMigrainereflectance confocal microscopy

Atogepant Shows Better Tolerability and Efficacy Than Topiramate in Migraine Prevention: TEMPLE Trial Results

By MedXY|Jul 26, 2026

The phase 3b TEMPLE trial found that atogepant 60 mg once daily led to fewer discontinuations due to adverse events and better migraine reduction than topiramate over 24 weeks.

Postmenopausal Migraine Signals Higher Ischemic Stroke Risk, Not Hemorrhagic Stroke, in the Women’s Health Initiative
NeurologyWomen’s Health InitiativeMigraine

Postmenopausal Migraine Signals Higher Ischemic Stroke Risk, Not Hemorrhagic Stroke, in the Women’s Health Initiative

By MedXY|Jun 10, 2026

In a large cohort of postmenopausal women, migraine history was associated with a modest increase in ischemic stroke risk over 20 years, while total and hemorrhagic stroke risks were not significantly elevated.

A Pain-Predominant Dry Eye Phenotype Emerges: Severe Symptoms, Few Ocular Signs, and Strong Links to Migraine and Psychiatric Disease
Neurologydry eye diseaseMigraine

A Pain-Predominant Dry Eye Phenotype Emerges: Severe Symptoms, Few Ocular Signs, and Strong Links to Migraine and Psychiatric Disease

By MedXY|Jun 1, 2026

A 2026 Ophthalmology report identified a pain-predominant dry eye phenotype in 6.9% of patients, marked by high symptom burden, minimal surface signs, and enrichment for migraine and psychiatric comorbidity.

Neural Connectivity Patterns Predict Acupuncture Response in Migraine: A Step Toward Personalized Pain Management
NeurologyacupuncturefMRI

Neural Connectivity Patterns Predict Acupuncture Response in Migraine: A Step Toward Personalized Pain Management

By MedXY|Feb 10, 2026

This randomized clinical trial demonstrates that real acupuncture significantly reduces migraine frequency and disability compared to sham acupuncture. Crucially, baseline brain connectivity patterns within the default mode and subcortical

Candesartan 16 mg Emerges as a Robust, Evidence-Based Option for Migraine Prophylaxis
NeurologyCandesartanMigraine

Candesartan 16 mg Emerges as a Robust, Evidence-Based Option for Migraine Prophylaxis

By MedXY|Dec 23, 2025

A Phase 2 triple-blind trial confirms that 16 mg of candesartan daily significantly reduces monthly migraine days compared to placebo, offering a well-tolerated oral alternative for patients with episodic migraine.

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