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Liver transplantation offers superior long-term survival compared to resection for combined hepatocellular-cholangiocarcinoma, with outcomes comparable to hepatocellular carcinoma when selecting patients without vascular invasion or poor di
Using organs from Trypanosoma cruzi-positive donors expands transplant availability in endemic regions but necessitates vigilant monitoring to manage Chagas disease reactivation safely.
This study evaluates different machine preservation strategies in donation after circulatory death (DCD) liver transplantation, highlighting their impact on graft outcomes, particularly nonanastomotic biliary strictures and survival rates,
In hospitalized patients with cirrhosis awaiting liver transplant, the AM-PAC “6-Clicks” Basic Mobility Score correlates strongly with both pretransplant waitlist mortality and posttransplant survival, offering a practical risk
MASLD has become a leading cause of liver transplantation in the US, with increasing transplant volumes and younger recipients. Despite relative stabilization in growth, survival post-transplant has improved, highlighting evolving epidemiol
This article analyzes global liver transplantation disparities relative to cirrhosis and chronic liver disease burden, revealing unequal access dominated by high-income countries and highlighting the role of health system development in tra
Poor food access correlates with higher MASLD and frailty prevalence in liver transplant candidates, with geospatial clustering highlighting socioeconomic and environmental determinants impacting transplant candidacy and outcomes.
This analysis of over 63,000 US liver transplants reveals that simultaneous liver-kidney transplantation (SLKT) confers significant survival benefit only in patients with severe renal dysfunction (eGFR <30), with no advantage in those wi
Complete pathologic response (cPR) after locoregional therapies notably improves survival in hepatocellular carcinoma (HCC) patients undergoing liver transplantation. Yttrium-90 radioembolization shows superior cPR rates, particularly when
This review synthesizes recent evidence on immune checkpoint inhibitor (ICI)-based downstaging therapy for hepatocellular carcinoma (HCC) beyond Milan criteria prior to liver transplantation, highlighting improved oncologic outcomes alongsi
This article reviews how hypothermic oxygenated and normothermic machine perfusion reduce hepatic and systemic inflammation after liver transplantation, improving immune regulation and clinical outcomes.
Medicaid expansion is associated with improved graft and patient survival following adult liver transplantation, highlighting the benefits of broader health insurance access on transplant outcomes.
This study reveals that liver transplant recipients exhibit significantly reduced lung function and increased dyspnea compared to the general population, highlighting the need for heightened pulmonary surveillance in this vulnerable group.
This study compares normothermic machine perfusion and normothermic regional perfusion in DCD liver transplants, demonstrating both advanced methods approach brain death graft survival and improve outcomes over static cold storage.
The Laennec technique offers a structured, anatomy-based robotic approach for right donor hepatectomies, demonstrating safety, feasibility, and zero biliary complications, potentially standardizing this complex procedure across centers.
A Swedish national retrospective study reveals that liver transplantations initiated between 17:00 and 05:59 are linked to significantly increased postoperative complications and healthcare costs, highlighting the need for optimized schedul
The Integrative Muscle-Adipose Score (IMAS) combines muscle and fat measures into a sex-specific tool that accurately predicts long-term survival and postoperative complications in liver transplant recipients, outperforming existing models.
This international cohort study evaluates hypothermic oxygenated perfusion (HOPE) versus normothermic machine perfusion (NMP) in liver transplantation, revealing comparable high graft survival despite differing donor risk profiles and highl
Liver transplantation facilitates early neurocognitive recovery in end-stage liver disease patients by restoring cortical network activities, with S-methyl-5′-thioadenosine playing a pivotal neuroprotective role through modulating neu
Pre-liver transplantation elevated serum renin levels correlate with increased intraoperative vasopressor use and postoperative acute kidney injury, suggesting its potential as a predictive biomarker for perioperative management and renal r
