Advancing Donation After Circulatory Death Liver Transplants: Comparing Normothermic Machine and Regional Perfusion Outcomes
donation after circulatory deathgraft survivalliver transplantationnormothermic machine perfusionnormothermic regional perfusion
Highlight
- Normothermic machine perfusion (NMP) and normothermic regional perfusion (NRP) improve 2-year graft survival in donation after circulatory death (DCD) liver transplants, closing the gap versus donation after brain death (DBD) grafts.
- Both NMP and NRP demonstrate comparable graft survival outcomes when directly compared using propensity score matching.
- Static cold storage (SCS) of DCD livers is associated with significantly increased graft loss and ischemic cholangiopathy risk.
- Advanced perfusion techniques should be routinely considered to optimize DCD liver transplant outcomes.
Study Background
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.