Elevated Preoperative Serum Renin Predicts Vasopressor Need and Acute Kidney Injury in Liver Transplant Patients
Highlight
- Serum renin can be elevated up to 100-fold prior to liver transplantation in patients with cirrhosis.
- Preoperative renin levels strongly correlate with intraoperative vasopressor requirements during the dissection phase, measured in norepinephrine equivalents.
- Elevated renin predicts postoperative acute kidney injury independent of preexisting renal function, while no association with early allograft dysfunction was observed.
- Measurement of serum renin may guide individualized vasopressor strategies, including consideration of angiotensin II infusion during liver transplantation.
Study Background
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.