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Family History as a Dose-Dependent Risk Factor for Postpartum Venous Thromboembolism: Insights from a Nationwide Swedish Cohort Study
Hematology-Oncologyfamily historygenetic risk

Family History as a Dose-Dependent Risk Factor for Postpartum Venous Thromboembolism: Insights from a Nationwide Swedish Cohort Study

By MedXY|Oct 13, 2026

This study reveals that family history significantly elevates postpartum venous thromboembolism risk in primiparous women, with risk proportional to genetic relatedness and number of affected relatives.

Reevaluating Colorectal Cancer Surveillance in Inflammatory Bowel Disease: The Role of Family History Beyond Early-Onset Cases
Gastroenterologycancer surveillance
family history

Reevaluating Colorectal Cancer Surveillance in Inflammatory Bowel Disease: The Role of Family History Beyond Early-Onset Cases

By MedXY|Sep 6, 2026

A nationwide cohort study reveals that in IBD patients, colorectal cancer risk increases notably with multiple affected relatives, challenging current guidelines prioritizing early-onset family history for surveillance.

Assessing Cardiovascular Risk in First-Degree Relatives of Individuals with Elevated Lipoprotein(a): Insights from a Swedish Cohort Study
Cardiologycardiovascular riskfamily history

Assessing Cardiovascular Risk in First-Degree Relatives of Individuals with Elevated Lipoprotein(a): Insights from a Swedish Cohort Study

By MedXY|Jul 12, 2026

A cohort study demonstrates increased major cardiovascular event risk in first-degree relatives of individuals with high plasma lipoprotein(a), supporting cascade screening for targeted prevention.

Family History Misses Actionable Germline Variants in Many Ovarian Cancer Patients Over 70
newsgermline testingovarian cancer

Family History Misses Actionable Germline Variants in Many Ovarian Cancer Patients Over 70

By MedXY|May 13, 2026

A large real-world registry study shows that ovarian cancer patients aged 70 and older still carry clinically actionable germline variants, often without a reported family history, supporting broader age-inclusive genetic testing.

Refining Prostate Cancer Risk Prediction in Men of African Ancestry: Integrating Pathogenic Variants, Polygenic Scores, and Family History
newsAfrican ancestryfamily history

Refining Prostate Cancer Risk Prediction in Men of African Ancestry: Integrating Pathogenic Variants, Polygenic Scores, and Family History

By MedXY|Dec 17, 2025

This study identifies key germline variants and demonstrates how combining genetic data with family history improves personalized prostate cancer risk assessment in men of African ancestry, guiding future screening strategies.

Quantifying Breast Cancer Risk: The Impact of Pathogenic Variants and Family History in US Women
newsbreast cancerfamily history

Quantifying Breast Cancer Risk: The Impact of Pathogenic Variants and Family History in US Women

By MedXY|Oct 10, 2025

This study evaluates cumulative breast cancer risks among US women based on pathogenic variant status and family history, revealing significant risk stratification that informs personalized screening and prevention.

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