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The 2026 EULAR update modernizes how recommendations and points-to-consider for rheumatic and musculoskeletal diseases are developed — formalizing patient partnership, living guidance, robust evidence synthesis, cost-awareness and transpare
A novel educational model embedding clinical research training within real-world trials improves medical students’ research skills, fosters evidence-based thinking, and bridges clinical and academic integration.
This article explores the integration of evidence-based medicine and personalized approaches in managing heart failure and inherited cardiomyopathies, proposing a framework to optimize patient care by harmonizing standardized guidelines wit
A comprehensive evidence-based synthesis of the REMAP-CAP trial and major international RCTs, demonstrating that ivermectin fails to improve clinical outcomes, survival, or organ support requirements in hospitalized and non-hospitalized COV
A cross-sectional study of 37 RCOG Green-Top Guidelines reveals that 24% lack Grade A recommendations, while those with highest-level evidence show limited consideration of health equity and generalisability in supporting studies, highlight
A comprehensive meta-analysis of double-blind RCTs by the CTT Collaboration reveals that the majority of adverse effects listed on statin labels, including cognitive and sleep issues, lack causal evidence, suggesting a need for urgent regul
A large-scale quasi-experimental study of over 171,000 ICU admissions found that routine magnesium supplementation for patients near institutional treatment thresholds does not reduce the risk of tachyarrhythmias, hypotension, or mortality,