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This study reveals that diabetes-related genetic risk scores predict pre-transplant diabetes status and influence metabolic outcomes one year after total pancreatectomy with islet autotransplantation in chronic pancreatitis patients.
A Europe-wide prospective study shows wide variation in morphology-based surgery for chronic pancreatitis and no clear outcome advantage from current guideline concordance — underscoring the need for unified, clearer recommendations on rese
A new multimodal study links regular physical activity to lower chronic pancreatitis risk and identifies muscle-derived extracellular vesicles as a plausible mechanism limiting pancreatic inflammation, fibrosis, and ferroptosis.
This review synthesizes recent evidence from the UK Biobank and molecular studies demonstrating that physical activity, particularly resistance exercise, restrains chronic pancreatitis by delivering muscle-derived extracellular vesicles tha
A five-RNA extracellular vesicle signature showed strong diagnostic performance for chronic pancreatitis and may also reflect acinar-to-ductal metaplasia and disease-related metabolic features.
This article synthesizes current understanding of type 3c diabetes (T3cDM) caused by chronic pancreatitis—covering pathophysiology (islet loss, exocrine insufficiency, altered incretin and hepatic/peripheral insulin sensitivity), diagnostic