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Despite nearly universal insurance coverage, nearly half of patients with distal upper extremity nerve injuries face significant financial hardship, influenced by injury location, surgical complexity, and preexisting debt. Targeted financia
First MTPJ arthrodesis significantly reduces walking pain at 12 months in hallux rigidus patients compared with watchful waiting, demonstrating a clinically meaningful benefit in this common foot osteoarthritis.
This study reveals that even amateur soccer heading causes immediate, transient increases in blood biomarkers p-tau217 and S100B, indicating acute neural impact and suggesting a dose-response effect.
This article explores personalized osteoporosis management, combining evidence-based pharmacologic therapies with individualized lifestyle and nutrition guidance, to improve patient outcomes through shared decision making.
This study demonstrates that hyperthyroidism driven by constitutively active TSH receptor mutations alters craniofacial structure and bone mineral density in mice, offering insights into thyroid hormone’s role in skeletal development.
A multicenter randomized trial found that 4-week multimodal prehabilitation added to ERAS reduced 90-day complications after spinal fusion in adults aged 75 years or older.
A multicenter trauma study found that 20.1% of surgically treated Morel-Lavallée lesions developed wound complications. Pedestrian-versus-vehicle injury was the only independent predictor of postoperative problems.
A small human cohort study suggests that upper extremity amputation with AMI reconstruction is feasible and may preserve residual limb volume, improve muscle mechanics, and reduce pain and phantom limb symptoms.
A survey study found three distinct patient preference patterns for anticoagulation after hip or knee replacement: clot-prevention focused, balanced, and cost-focused. These differences may help personalize postoperative blood thinner choic
A survey study found three distinct patient preference patterns for anticoagulation after hip or knee replacement, highlighting the importance of shared decision-making based on clot risk, bleeding risk, and cost.
A recent randomized trial found PT modestly improved function over CBT in cLBP, but no second-stage treatment differences emerged for nonresponders. The study informs adaptive treatment strategies.
This review analyzes the LIDA trial findings, demonstrating that an abbreviated 3-month romosozumab course followed by denosumab is non-inferior to the standard 12-month regimen in increasing total hip bone mineral density, potentially redu
This review evaluates the LIDA trial’s findings that 3 months of romosozumab followed by denosumab is non-inferior to 12 months of romosozumab, offering a cost-effective strategy to mitigate long-term side effects.
A Phase 3 pragmatic trial found that 12 hours of weekly intensive task-specific training added to usual care does not improve motor recovery in recent spinal cord injury patients, suggesting a potential plateau in the benefits of early reha
Recent clinical evidence demonstrates that endoscopic and arthroscopic techniques for infraclavicular brachial plexus neurolysis and pectoralis minor release provide comparable outcomes to open surgery with significantly reduced morbidity f
A multicenter randomized trial shows diacerein provides no clinical benefit over placebo for knee pain in patients with MRI-confirmed inflammation, despite its theoretical role as an IL-1β blocker.
A randomized clinical trial demonstrates that while CYP2D6 genotyping significantly shifts opioid prescribing patterns for poor and intermediate metabolizers, it does not improve pain control or reduce opioid consumption within the context
The PROP OA trial demonstrates that adding compartment-specific knee bracing and adherence support to standard exercise and advice significantly improves pain and function in patients with knee osteoarthritis, offering a safe and effective
The SCIENCE multicentre randomized trial demonstrates that surgical fixation for displaced medial epicondyle fractures in children provides no functional advantage over non-surgical care, carries higher complication risks, and is not a cost
A 5-year randomized controlled trial reveals that combining ACL reconstruction with anterolateral ligament (ALL) reconstruction using hamstring autograft significantly outperforms bone-patellar tendon-bone autograft alone, reducing graft fa
