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Bridging Evidence-Based and Personalized Medicine in Heart Failure and Cardiomyopathies: Balancing Standardization with Individualization
CardiologyY học dựa trên bằng chứngheart failure

Bridging Evidence-Based and Personalized Medicine in Heart Failure and Cardiomyopathies: Balancing Standardization with Individualization

By MedXY|Sep 17, 2026

This article explores the integration of evidence-based medicine and personalized approaches in managing heart failure and inherited cardiomyopathies, proposing a framework to optimize patient care by harmonizing standardized guidelines wit

Ivermectin for COVID-19: From Pandemic Controversy to Definitive Futility in the REMAP-CAP and Global Randomized Trials
Clinical Updates
clinical trials
COVID-19

Ivermectin for COVID-19: From Pandemic Controversy to Definitive Futility in the REMAP-CAP and Global Randomized Trials

By MedXY|May 12, 2026

A comprehensive evidence-based synthesis of the REMAP-CAP trial and major international RCTs, demonstrating that ivermectin fails to improve clinical outcomes, survival, or organ support requirements in hospitalized and non-hospitalized COV

Evidence Gaps in Maternity Guidelines: RCOG Green-Top Guidelines Show Limited Health Equity Considerations in High-Quality Recommendations
newsclinical guidelineshealth equity

Evidence Gaps in Maternity Guidelines: RCOG Green-Top Guidelines Show Limited Health Equity Considerations in High-Quality Recommendations

By MedXY|Apr 9, 2026

A cross-sectional study of 37 RCOG Green-Top Guidelines reveals that 24% lack Grade A recommendations, while those with highest-level evidence show limited consideration of health equity and generalisability in supporting studies, highlight

Challenging the Label: Large-Scale Meta-Analysis Refutes Most Statin-Attributed Adverse Effects
CardiologyCardiologypharmacovigilance

Challenging the Label: Large-Scale Meta-Analysis Refutes Most Statin-Attributed Adverse Effects

By MedXY|Feb 16, 2026

A comprehensive meta-analysis of double-blind RCTs by the CTT Collaboration reveals that the majority of adverse effects listed on statin labels, including cognitive and sleep issues, lack causal evidence, suggesting a need for urgent regul

Routine Magnesium Replacement in the ICU: Challenging the Dogma of Tachyarrhythmia Prevention
Cardiologycritical careY học dựa trên bằng chứng

Routine Magnesium Replacement in the ICU: Challenging the Dogma of Tachyarrhythmia Prevention

By MedXY|Jan 1, 2026

A large-scale quasi-experimental study of over 171,000 ICU admissions found that routine magnesium supplementation for patients near institutional treatment thresholds does not reduce the risk of tachyarrhythmias, hypotension, or mortality,

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