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Levothyroxine in Pregnancy for Subclinical Hypothyroidism or Hypothyroxinemia: No Benefit on Child IQ

By MedXY|Jul 28, 2026

A randomized trial found that levothyroxine treatment for subclinical hypothyroidism or hypothyroxinemia starting between 8 and 20 weeks of gestation did not improve IQ scores in children at age 5 years compared with placebo.

Prevalence and Clinical Characteristics of Macro-TSH in Patients with Subclinical Hypothyroidism

Diabetes & Endocrinologylevothyroxinemacro-TSH

subclinical hypothyroidism

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Levothyroxine in Pregnancy for Subclinical Hypothyroidism or Hypothyroxinemia: No Benefit on Child IQ

Prevalence and Clinical Characteristics of Macro-TSH in Patients with Subclinical Hypothyroidism

Long-Term Risk of Hypothyroidism After Thyroid Abnormalities Identified in Pregnancy

Thyroid Dysfunction Is a Cardiovascular Risk Multiplier, but Treatment Benefits Depend on Phenotype, Severity, and Age

Levothyroxine in the Ageing Patient: Re-evaluating Cardiovascular Outcomes in Subclinical Hypothyroidism through the ACEL-UK-ETT Trial

The Interplay of Aging and Chronic Iodine Excess on Thyrotropin Dynamics: A 20-Year Longitudinal Synthesis