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Stroke Disability and Mortality Post-ED Discharge for Dizziness: Rare but Clinically Significant

Stroke Disability and Mortality Post-ED Discharge for Dizziness: Rare but Clinically Significant

A retrospective cohort study reveals that stroke-related disability or mortality after ED discharge for dizziness is rare (0.04% incidence), with most lesions occurring in the anterior fossa. Findings underscore the need for targeted risk s

Section: Emergency MedicineApr 28, 2026

EVT Shows Superior Outcomes in Anterior Cerebral Artery Occlusion Stroke: Insights from the ORIENTAL-MeVO Registry

EVT Shows Superior Outcomes in Anterior Cerebral Artery Occlusion Stroke: Insights from the ORIENTAL-MeVO Registry

Endovascular thrombectomy (EVT) significantly improves 90-day functional outcomes in acute anterior cerebral artery occlusion stroke compared to standard medical management, without increasing hemorrhage or mortality risks, per the ORIENTAL

Section: NeurologyApr 26, 2026

Inflammatory Biomarkers in Cerebral Venous Thrombosis: Prognostic Insights from the CLOT-VENUS Substudy and Meta-Analyses

Inflammatory Biomarkers in Cerebral Venous Thrombosis: Prognostic Insights from the CLOT-VENUS Substudy and Meta-Analyses

High admission levels of NLR, PLR, MLR, and SII are independently associated with poor functional outcomes and mortality in acute cerebral venous thrombosis, offering a low-cost tool for early risk stratification.

Section: Clinical UpdatesApr 24, 2026

Real-Time fMRI Neurofeedback Shows Promise for Reading Rehabilitation in Post-Stroke Aphasia

Real-Time fMRI Neurofeedback Shows Promise for Reading Rehabilitation in Post-Stroke Aphasia

This feasibility RCT demonstrates that contingent fMRI neurofeedback targeting the left supramarginal gyrus can improve reading comprehension in stroke survivors with aphasia, outperforming both healthy controls and non-contingent neurofeed

Section: NeurologyApr 14, 2026

Mobile Health Intervention Achieves 24% Better Blood Pressure Control in Stroke Survivors: PINGS Trial Results from Ghana

Mobile Health Intervention Achieves 24% Better Blood Pressure Control in Stroke Survivors: PINGS Trial Results from Ghana

The PINGS trial demonstrates that a 12-month nurse-led mobile health intervention significantly improves blood pressure control among Ghanaian stroke survivors, with 67% achieving target BP versus 43% in usual care. This pragmatic approach

Section: CardiologyApr 13, 2026

Optimizing Prehospital Pathways: Impact of the Iranian Comprehensive Code Stroke Management Program (ICSM Phase III) on Thrombolysis Rates

Optimizing Prehospital Pathways: Impact of the Iranian Comprehensive Code Stroke Management Program (ICSM Phase III) on Thrombolysis Rates

This review analyzes the ICSM Phase III study, highlighting how a structured empowerment program and standardized protocols in EMS significantly reduced prehospital delays and tripled alteplase administration rates for acute ischemic stroke

Section: Clinical UpdatesMar 12, 2026

Impact of the FKBP5 Gene on Stroke Recovery: A Comparative Study in Mice and Humans

Impact of the FKBP5 Gene on Stroke Recovery: A Comparative Study in Mice and Humans

This translational study demonstrates that the FKBP5 protein, a regulator of the stress response, significantly influences stroke outcomes. Lower FKBP5 levels correlate with smaller brain lesions in mice, while high-expression genetic varia

Section: NeurologyMar 11, 2026

Perihematomal Edema Dynamics and Functional Outcomes in Spontaneous Intracerebral Hemorrhage: Insights from a Global IPD Meta-Analysis

Perihematomal Edema Dynamics and Functional Outcomes in Spontaneous Intracerebral Hemorrhage: Insights from a Global IPD Meta-Analysis

This article synthesizes evidence from a large-scale individual participant data meta-analysis, demonstrating that early perihematomal edema growth (at 24 and 72 hours) is an independent predictor of death and disability after intracerebral

Section: Clinical UpdatesMar 10, 2026

Beyond the Binary: The Evolving Consensus on the Spectrum of Primary Aldosteronism and Cardiovascular Risk

Beyond the Binary: The Evolving Consensus on the Spectrum of Primary Aldosteronism and Cardiovascular Risk

Recent data from the ARIC study and emerging expert consensus are redefining primary aldosteronism. Rather than a rare, all-or-nothing condition, it is now viewed as a broad spectrum where even subclinical elevations significantly increase

Section: CardiologyMar 7, 2026

Antiepileptogenesis After Stroke: Assessing the Impact of Eslicarbazepine Acetate on Seizure Prevention

Antiepileptogenesis After Stroke: Assessing the Impact of Eslicarbazepine Acetate on Seizure Prevention

This article examines a Phase 2a trial investigating eslicarbazepine acetate for preventing post-stroke epilepsy. While the primary endpoint was not met due to recruitment challenges, the study provides a critical framework for future antie

Section: NeurologyMar 7, 2026

The Rising Tide of Cardiovascular Disease: AHA’s 2050 Forecast for Women’s Heart Health

The Rising Tide of Cardiovascular Disease: AHA’s 2050 Forecast for Women’s Heart Health

A major AHA scientific statement forecasts a significant increase in cardiovascular disease and risk factors among U.S. women by 2050. It highlights rising rates of obesity and hypertension while emphasizing the urgent need for targeted int

Section: CardiologyMar 2, 2026

Minocycline Significantly Improves Functional Recovery in Acute Ischaemic Stroke: Evidence from the EMPHASIS Trial

Minocycline Significantly Improves Functional Recovery in Acute Ischaemic Stroke: Evidence from the EMPHASIS Trial

The EMPHASIS trial reveals that oral minocycline initiated within 72 hours of an acute ischaemic stroke significantly enhances functional independence at 90 days. This multicentre study provides robust evidence for a well-tolerated, accessi

Section: Internal MedicineMar 2, 2026

Adversity Across the Lifespan: The Compounding Impact of Childhood and Adult Stress on Dementia and Stroke Risk

Adversity Across the Lifespan: The Compounding Impact of Childhood and Adult Stress on Dementia and Stroke Risk

This population-based cohort study highlights how cumulative psychosocial stress across the life course significantly escalates the risk of neurovascular and neurodegenerative diseases, identifying depression as a critical target for interv

Section: NeurologyFeb 12, 2026

Time-Dependent Topography: How Specific ASPECTS Regions Predict Outcomes in Early vs. Extended Window Large Vessel Occlusion Stroke

Time-Dependent Topography: How Specific ASPECTS Regions Predict Outcomes in Early vs. Extended Window Large Vessel Occlusion Stroke

A post-hoc analysis of 1,040 LVO stroke patients reveals that the prognostic value of specific brain regions varies significantly between early (0-6h) and extended (6-24h) time windows, identifying the insula, caudate, and M6 as early-windo

Section: NeurologyFeb 4, 2026

Tenecteplase Fails to Improve Visual Outcomes in Acute Central Retinal Artery Occlusion: Results from the TenCRAOS Trial

Tenecteplase Fails to Improve Visual Outcomes in Acute Central Retinal Artery Occlusion: Results from the TenCRAOS Trial

The TenCRAOS trial demonstrated that intravenous tenecteplase administered within 4.5 hours of acute central retinal artery occlusion does not improve vision recovery compared to aspirin and carries significant safety risks, including fatal

Section: NeurologyFeb 2, 2026

Predicting Stroke Recurrence: MRI Markers Outperform Location in Risk-Stratifying Patients with ICH and Atrial Fibrillation

Predicting Stroke Recurrence: MRI Markers Outperform Location in Risk-Stratifying Patients with ICH and Atrial Fibrillation

A secondary analysis of the PRESTIGE-AF trial reveals that specific MRI markers, including cortical superficial siderosis and macrohemorrhages, are more potent predictors of recurrent intracerebral hemorrhage than hematoma location alone, o

Section: CardiologyJan 21, 2026

Long-Term Gains vs. Short-Term Risks: Decoding the Role of Bailout Angioplasty in Acute Large Vessel Occlusion

Long-Term Gains vs. Short-Term Risks: Decoding the Role of Bailout Angioplasty in Acute Large Vessel Occlusion

The ANGEL-REBOOT trial reveals that while bailout angioplasty (BAOS) increases short-term procedural risks, it significantly improves one-year functional outcomes and reduces stroke recurrence in patients with failed thrombectomy or high-gr

Section: NeurologyJan 18, 2026

Routine Cerebral Embolic Protection Fails to Mitigate Stroke or Cognitive Decline in TAVI: Results from the BHF PROTECT-TAVI Trial

Routine Cerebral Embolic Protection Fails to Mitigate Stroke or Cognitive Decline in TAVI: Results from the BHF PROTECT-TAVI Trial

The landmark BHF PROTECT-TAVI trial reveals that cerebral embolic protection (CEP) does not reduce periprocedural stroke or cognitive impairment following TAVI. This large-scale study challenges the routine use of embolic filters, suggestin

Section: CardiologyJan 18, 2026

Pushing the Limits: Very Low LDL-C Levels Below 40 mg/dL Proven Safe and Effective for Secondary Stroke Prevention

Pushing the Limits: Very Low LDL-C Levels Below 40 mg/dL Proven Safe and Effective for Secondary Stroke Prevention

A long-term analysis of the FOURIER trials reveals that achieving ultra-low LDL-C levels (

Section: NeurologyJan 18, 2026

Decompressive Craniectomy Benefits Persist Across Deep Intracerebral Hemorrhage Locations: A SWITCH Trial Analysis

Decompressive Craniectomy Benefits Persist Across Deep Intracerebral Hemorrhage Locations: A SWITCH Trial Analysis

A post hoc analysis of the SWITCH trial demonstrates that the clinical benefits of decompressive craniectomy in reducing death and severe disability are consistent across different anatomical locations of deep supratentorial intracerebral h

Section: Critical CareJan 18, 2026

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