Early Recanalization in Distal and Medium Vessel Occlusion Strokes: Tenecteplase vs Alteplase

Highlight

• Tenecteplase demonstrated significantly higher early successful recanalization rates in distal and medium vessel occlusion strokes compared to alteplase.
• Patients treated with tenecteplase experienced notably less substantial early infarct growth, indicating potential neuroprotective benefits.
• The study supports tenecteplase as a preferable intravenous thrombolytic agent in DMVO strokes where endovascular thrombectomy is not pursued.

Study Background