Hematology-Oncologypediatric AMLMetabolic Reprogramming
Mitochondrial Transfer via Tunneling Nanotubes: A Novel Mechanism of Macrophage-Mediated Immunosuppression in Pediatric AML
By MedXY|Oct 19, 2026
Mitochondrial transfer from pediatric AML blasts to macrophages via tunneling nanotubes induces metabolic and immunosuppressive reprogramming, impairing anti-leukemic immune responses and supporting chemoresistance, revealing potential targ