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Evaluating Beta Cell Function in Preclinical Type 1 Diabetes Using CGM-Derived Disposition Index
Diabetes & EndocrinologyBeta-cell functioncontinuous glucose monitoring

Evaluating Beta Cell Function in Preclinical Type 1 Diabetes Using CGM-Derived Disposition Index

By MedXY|Oct 14, 2026

A novel CGM-derived disposition index reliably estimates beta cell function in individuals with islet autoimmunity without insulin therapy, predicting glycemic deterioration one year later.

Unraveling Maternal Protection Against Type 1 Diabetes: Genetic Risk and Intrauterine Influences
Diabetes & EndocrinologyGenetic Risk ScoreIslet Autoimmunity
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Unraveling Maternal Protection Against Type 1 Diabetes: Genetic Risk and Intrauterine Influences

By MedXY|Oct 7, 2026

This study reveals that the reduced risk of type 1 diabetes in children born to mothers with the condition is not due to genetic differences but possibly to protective intrauterine exposures during early childhood.

Rising Incidence of Islet Autoimmunity Among Colorado Children With Moderate-Risk HLA Genotypes: Insights From Longitudinal Cohorts
Diabetes & EndocrinologyepidemiologyIslet Autoimmunity

Rising Incidence of Islet Autoimmunity Among Colorado Children With Moderate-Risk HLA Genotypes: Insights From Longitudinal Cohorts

By MedXY|Sep 11, 2026

A study reveals a significant secular increase in islet autoimmunity incidence among Colorado children from 1993 to 2010, particularly in those with moderate-risk HLA genotypes, highlighting evolving risk profiles beyond known environmental

Fecal Short-Chain Fatty Acids in Mother-Infant Dyads: No Direct Link to Islet Autoimmunity Development
Diabetes & Endocrinologygut microbiometype 1 diabetes

Fecal Short-Chain Fatty Acids in Mother-Infant Dyads: No Direct Link to Islet Autoimmunity Development

By MedXY|Aug 24, 2026

A longitudinal study shows no association between fecal short-chain fatty acid levels during pregnancy and early childhood with the progression to islet autoimmunity in children at risk for type 1 diabetes.

Lifestyle Determinants and Metabolic Compensation in Pregnancies Complicated by Type 1 Diabetes: A Synthesis of the ENDIA Study and Recent Evidence
Clinical UpdatesIslet Autoimmunitynutrition

Lifestyle Determinants and Metabolic Compensation in Pregnancies Complicated by Type 1 Diabetes: A Synthesis of the ENDIA Study and Recent Evidence

By MedXY|Mar 12, 2026

This review analyzes the lifestyle patterns of pregnant women with type 1 diabetes, synthesizing findings from the ENDIA study with recent evidence on nutritional adequacy, islet autoimmunity, and the molecular mechanisms of metabolic compe

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