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Reevaluating Calcineurin Inhibitor Use in Identical Twin Kidney Transplants: Are We Overmedicating?
Internal Medicinegraft survivalimmunosuppression

Reevaluating Calcineurin Inhibitor Use in Identical Twin Kidney Transplants: Are We Overmedicating?

By MedXY|Sep 4, 2026

Despite identical immunogenetic makeup, half of kidney transplant recipients from identical twins remain on calcineurin inhibitors, with no demonstrable benefit in rejection reduction or graft survival over 25 years, calling for critical re

Determinants of One-Year Success in Descemet Membrane Endothelial Keratoplasty: Insights from the Diabetes Endothelial Keratoplasty Study
Diabetes & Endocrinologycorneal transplantationdiabetes

Determinants of One-Year Success in Descemet Membrane Endothelial Keratoplasty: Insights from the Diabetes Endothelial Keratoplasty Study

By MedXY|Aug 2, 2026

This article examines factors influencing the one-year success rate of DMEK in treating corneal endothelial dysfunction, highlighting the impact of operative complications and donor-recipient variables based on findings from the Diabetes En

Advancing Donation After Circulatory Death Liver Transplantation: National Evidence Supporting Normothermic Regional and Machine Perfusion as Standards of Care
GastroenterologyDCD liver transplantationgraft survival

Advancing Donation After Circulatory Death Liver Transplantation: National Evidence Supporting Normothermic Regional and Machine Perfusion as Standards of Care

By MedXY|Jun 25, 2026

A comprehensive national study shows both normothermic regional perfusion (NRP) and normothermic machine perfusion (NMP) significantly improve graft survival in DCD liver transplantation, supporting their adoption as complementary standards

Impact of Normothermic Regional Perfusion on Outcomes in Kidney Transplantation From Donors After Circulatory Death
NephrologyDCDdelayed graft function

Impact of Normothermic Regional Perfusion on Outcomes in Kidney Transplantation From Donors After Circulatory Death

By MedXY|Jun 4, 2026

In a nationwide U.S. analysis of 21,010 adult DCD kidney transplants, normothermic regional perfusion lowered delayed graft function, shortened hospital stay, and improved graft and patient survival, with the greatest benefit in higher-risk

The Age Gap Penalty: Why Donor-Recipient Mismatch Shortens Graft Life in Adolescent Liver Transplants
Gastroenterologygraft survivalliver transplant

The Age Gap Penalty: Why Donor-Recipient Mismatch Shortens Graft Life in Adolescent Liver Transplants

By MedXY|Feb 10, 2026

A nationwide study reveals that adolescent liver transplant recipients receiving grafts from donors 10+ years older face a 12.7% reduction in 10-year graft survival. Expanding allocation radii could improve access to age-matched organs and

Expanding Donor Pools: Outcomes of Liver Transplantation Using Grafts from Medical Assistance in Dying Donors in Canada
Gastroenterologydonation after circulatory deathgraft survival

Expanding Donor Pools: Outcomes of Liver Transplantation Using Grafts from Medical Assistance in Dying Donors in Canada

By MedXY|Oct 31, 2025

This Canadian multicenter study evaluates liver transplant outcomes using grafts from donation after medical assistance in dying donors, showing comparable survival and complication rates to standard donors and increasing transplant activit

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