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Switching from Mepolizumab to Benralizumab in EGPA: A Promising Alternative for Persistent Respiratory Symptoms
RheumatologyBenralizumabEGPA

Switching from Mepolizumab to Benralizumab in EGPA: A Promising Alternative for Persistent Respiratory Symptoms

By MedXY|Oct 23, 2026

In EGPA patients unresponsive to mepolizumab, switching to benralizumab improves lung function, reduces glucocorticoid use, and shows a favorable safety profile, suggesting its potential as an effective alternative treatment.

Rituximab Shows No Superiority Over Conventional Therapy for EGPA Remission Induction
Clinical UpdatesEGPARituximab

Rituximab Shows No Superiority Over Conventional Therapy for EGPA Remission Induction

By MedXY|Jul 31, 2025

A phase 3 randomized trial found rituximab no more effective than standard glucocorticoid-based therapy in inducing remission in eosinophilic granulomatosis with polyangiitis (EGPA), with comparable safety and relapse profiles.

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