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Timing Matters: Delayed Statin Initiation After Incidental High LDL-C Detection Significantly Increases Myocardial Infarction Risk

Timing Matters: Delayed Statin Initiation After Incidental High LDL-C Detection Significantly Increases Myocardial Infarction Risk

A large-scale cohort study demonstrates that delaying statin therapy following the incidental discovery of high LDL-C during routine health screenings leads to a progressively higher risk of myocardial infarction, emphasizing the critical i

Section: CardiologyJan 4, 2026

Beyond the Golden Years: Young COPD and Early Lung Function Decline as Critical Drivers of Premature Mortality and Cardiovascular Risk

Beyond the Golden Years: Young COPD and Early Lung Function Decline as Critical Drivers of Premature Mortality and Cardiovascular Risk

Recent evidence reveals that COPD in adults under 50 is more prevalent than previously thought, significantly increasing the risk of premature death and heart failure. Furthermore, impaired lung function trajectories starting in childhood p

Section: Internal MedicineJan 1, 2026

AI-Detected Coronary Calcium Significantly Predicts Cardiovascular Risk in Patients with Immune-Mediated Inflammatory Diseases

AI-Detected Coronary Calcium Significantly Predicts Cardiovascular Risk in Patients with Immune-Mediated Inflammatory Diseases

AI-driven analysis of routine chest CTs reveals that coronary artery calcium is highly prevalent and strongly predictive of MACE and mortality in patients with IMIDs, identifying a critical treatment gap in this high-risk population.

Section: AIDec 25, 2025

Beyond Insulin Resistance: Why Diabetes Status Dictates the Cardiovascular Risk of the Triglyceride-Glucose Index

Beyond Insulin Resistance: Why Diabetes Status Dictates the Cardiovascular Risk of the Triglyceride-Glucose Index

A prospective ARIC cohort study reveals that diabetes fundamentally modifies the relationship between the triglyceride-glucose (TyG) index and subclinical myocardial injury, shifting the risk profile from an L-shaped to a J-shaped associati

Section: CardiologyDec 25, 2025

Preoperative Cardiovascular Risk Does Not Dictate RAS Inhibitor Management: Insights from the STOP-or-NOT Trial

Preoperative Cardiovascular Risk Does Not Dictate RAS Inhibitor Management: Insights from the STOP-or-NOT Trial

A post hoc analysis of the STOP-or-NOT trial demonstrates that preoperative cardiovascular risk stratification does not influence the outcomes of continuing versus discontinuing renin-angiotensin system inhibitors before major noncardiac su

Section: AnesthesiologyDec 23, 2025

Long-Term Hormone Therapy in Menopausal Women: Balancing Benefits and Risks

Long-Term Hormone Therapy in Menopausal Women: Balancing Benefits and Risks

Updated Cochrane review shows mixed outcomes for long-term hormone therapy in peri- and postmenopausal women.

Section: CardiologyDec 16, 2025

Beyond the Lesion: Long-Term Cardiovascular, Neurologic, Psychiatric, and Endocrine Risks After Traumatic Spinal Cord Injury

Beyond the Lesion: Long-Term Cardiovascular, Neurologic, Psychiatric, and Endocrine Risks After Traumatic Spinal Cord Injury

A large retrospective cohort study shows traumatic spinal cord injury (TSCI) is associated with increased long-term cardiovascular, neurologic, psychiatric, and endocrine morbidity and higher mortality, even in previously healthy adults.

Section: CardiologyDec 15, 2025

Evaluating AHA PREVENT Equations and Lipoprotein(a) in Cardiovascular Risk Stratification: Integrative Insights from MESA and UK Biobank Cohorts

Evaluating AHA PREVENT Equations and Lipoprotein(a) in Cardiovascular Risk Stratification: Integrative Insights from MESA and UK Biobank Cohorts

This review synthesizes evidence on the performance of AHA PREVENT equations in individuals with elevated lipoprotein(a), emphasizing its independent risk association and potential to enhance personalized ASCVD risk prediction.

Section: CardiologyDec 3, 2025

High Cardiovascular Risk but Poor Risk-factor Control in Antiphospholipid Syndrome — Worse in Primary APS than SLE-related APS

High Cardiovascular Risk but Poor Risk-factor Control in Antiphospholipid Syndrome — Worse in Primary APS than SLE-related APS

A multinational cross-sectional study of 1003 people with antiphospholipid syndrome (APS) found high prevalence of hypertension, hyperlipidaemia, obesity and smoking, with suboptimal attainment of guideline targets — particularly among thos

Section: CardiologyNov 30, 2025

Genetic Liability to Hypertensive Disorders of Pregnancy Predicts Increased Long‑Term Cardiovascular Risk: Mendelian Randomization and Polygenic Risk Evidence

Genetic Liability to Hypertensive Disorders of Pregnancy Predicts Increased Long‑Term Cardiovascular Risk: Mendelian Randomization and Polygenic Risk Evidence

Genetic predisposition to preeclampsia and gestational hypertension is associated with higher risk of later-life cardiovascular disease; polygenic risk amplifies this risk, while obstetric history improves risk stratification beyond PRSs al

Section: CardiologyNov 29, 2025

Gender‑Affirming Hormone Therapy and Acute Cardiovascular Events: Dutch Cohort Finds Lower MI but Higher VTE in Transgender Women, Elevated MI and Stroke Risk in Transgender Men

Gender‑Affirming Hormone Therapy and Acute Cardiovascular Events: Dutch Cohort Finds Lower MI but Higher VTE in Transgender Women, Elevated MI and Stroke Risk in Transgender Men

A large Dutch cohort study found that after adjusting for socioeconomic status and lifestyle, transgender women on oestradiol had lower myocardial infarction (MI) risk but higher venous thromboembolism (VTE) risk; transgender men on testost

Section: CardiologyNov 29, 2025

Invisible Invaders: How Microplastics May Accelerate Atherosclerosis — and Why Men Could Be at Greater Risk

Invisible Invaders: How Microplastics May Accelerate Atherosclerosis — and Why Men Could Be at Greater Risk

New animal research links oral microplastic exposure to dramatic increases in arterial plaque—especially in males—by injuring endothelial cells and provoking inflammation and oxidative stress.

Section: CardiologyNov 25, 2025

Global CKD Now Affects 788 Million Adults (1990–2023): Rising Prevalence, Growing Mortality, and a Major Cardiovascular Risk

Global CKD Now Affects 788 Million Adults (1990–2023): Rising Prevalence, Growing Mortality, and a Major Cardiovascular Risk

The GBD 2023 analysis estimates 788 million adults living with chronic kidney disease in 2023, rising since 1990, with CKD a top-10 cause of death and a major contributor to cardiovascular mortality. Urgent action on screening, prevention,

Section: NephrologyNov 11, 2025

Even a Few Days of 4,000+ Steps Lowers Mortality and CVD Risk in Older Women — More Steps Still Better

Even a Few Days of 4,000+ Steps Lowers Mortality and CVD Risk in Older Women — More Steps Still Better

In >13,000 older women followed ≈11 years, achieving ≥4,000 steps on as little as 1–2 days/week was linked to lower all‑cause mortality and CVD; higher daily step thresholds produced additional benefit, but associations were driven largely

Section: CardiologyNov 4, 2025

Aspirin Use in Chronic Coronary Syndrome Patients on Oral Anticoagulation: Balancing Risks and Benefits

Aspirin Use in Chronic Coronary Syndrome Patients on Oral Anticoagulation: Balancing Risks and Benefits

A randomized trial revealed that adding aspirin to oral anticoagulation in chronic coronary syndrome patients increases adverse cardiovascular events, mortality, and major bleeding, challenging conventional dual therapy approaches.

Section: CardiologyOct 31, 2025

Impact of Diabetes on the Triglyceride-Glucose Index and Cardiovascular Outcomes in Coronary Heart Disease: A Comprehensive Meta-Analysis

Impact of Diabetes on the Triglyceride-Glucose Index and Cardiovascular Outcomes in Coronary Heart Disease: A Comprehensive Meta-Analysis

This meta-analysis of 36 cohort studies shows that higher triglyceride-glucose index levels predict increased risk of major adverse cardiovascular events in coronary heart disease patients, with differential effects observed by diabetes sta

Section: CardiologyOct 20, 2025

Comparing the PREVENT and PCE Models for 10-Year ASCVD Risk Prediction: Insights from a Large Real-World Cohort

Comparing the PREVENT and PCE Models for 10-Year ASCVD Risk Prediction: Insights from a Large Real-World Cohort

This review evaluates PREVENT versus PCE models for estimating 10-year ASCVD risk focusing on accuracy in patients with and without statin therapy, highlighting implications for personalized prevention.

Section: CardiologyOct 9, 2025

Long-Term Outcomes of the DASH Intervention in Nonobstructive Coronary Artery Disease: Follow-Up of the DISCO-CT Study

Long-Term Outcomes of the DASH Intervention in Nonobstructive Coronary Artery Disease: Follow-Up of the DISCO-CT Study

A one-year DASH diet intervention led to sustained suppression of proatherogenic chemokine CXCL4 and fewer major cardiovascular events over six years despite reduced adherence and partial loss of initial benefits in nonobstructive CAD patie

Section: CardiologyOct 8, 2025

The Hidden Vascular Assassin: How Homocysteine Independently Accelerates Atherosclerosis

The Hidden Vascular Assassin: How Homocysteine Independently Accelerates Atherosclerosis

Beyond cholesterol and blood pressure, homocysteine silently hardens arteries, driving cardiovascular disease progression independently—latest research reveals its biomechanical impact and prevention strategies.

Section: Medical NewsSep 14, 2025

CT Angiography Enhances Lifestyle and Prevention Uptake in Cardiovascular Risk Management: Insights from SCOT-HEART 2 Substudy

CT Angiography Enhances Lifestyle and Prevention Uptake in Cardiovascular Risk Management: Insights from SCOT-HEART 2 Substudy

A nested substudy from SCOT-HEART 2 reveals coronary CT angiography modestly improves healthy lifestyle adherence, preventive therapy acceptance, and risk factor modification compared to traditional cardiovascular risk scoring in asymptomat

Section: CardiologyOct 8, 2025

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