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Elevated Heart Failure Risk in People With HIV: Insights from the REPRIEVE Trial

MedXY Editorial Team•Apr 30, 2026•Cardiology
cardiovascular riskheart failureHIV

Background

People with HIV (PWH) face an elevated risk of cardiovascular diseases, including heart failure (HF), due to a combination of traditional risk factors and HIV-related mechanisms such as chronic inflammation and immune dysregulation. Despite advances in antiretroviral therapy (ART), the incidence and predictors of HF in PWH remain inadequately characterized. The REPRIEVE trial aimed to quantify HF risk in a global cohort of PWH with low-to-moderate atherosclerotic cardiovascular disease (ASCVD) risk.

Study Design

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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