Allogeneic Hematopoietic Stem Cell Transplantation

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Critical Careseptic shockAllogeneic Hematopoietic Stem Cell Transplantation

Septic Shock in Allogeneic Hematopoietic Stem-Cell Transplant Recipients: Outcomes, Prognostic Factors, and Clinical Implications from a Multicenter ICU Cohort

By MedXY|Sep 2, 2026

Septic shock following allogeneic hematopoietic stem-cell transplantation has a high 90-day mortality rate of 63%, strongly influenced by illness severity, fungal infection, and neutropenia. Early aminoglycoside use shows complex associatio

Allergy & ImmunologyIL-18Allogeneic Hematopoietic Stem Cell Transplantation

Divergent Roles of IL-12p40 and IL-18 in Severe Fibrosing Chronic Graft-versus-Host Disease: Implications for Immunity and Post-Transplant Outcomes

By MedXY|Aug 27, 2026

This study reveals distinct clinical associations of IL-12p40 and IL-18 in severe fibrosing chronic graft-versus-host disease, highlighting their differing impacts on relapse risk, survival, and immune responses post-allogeneic stem cell tr

Clinical UpdatesAllogeneic Hematopoietic Stem Cell Transplantation

Hetrombopag vs. Thrombopoietin for Platelet Engraftment After Allogeneic Stem Cell Transplantation: New Evidence from a Multicenter Randomized Controlled Trial

By MedXY|Aug 6, 2025

Hetrombopag demonstrates comparable efficacy and safety to thrombopoietin for platelet engraftment after allogeneic hematopoietic stem cell transplantation, offering a promising alternative in hematologic care.