Septic Shock in Allogeneic Hematopoietic Stem-Cell Transplant Recipients: Outcomes, Prognostic Factors, and Clinical Implications from a Multicenter ICU Cohort
Highlight
- Septic shock is a leading cause of ICU admission among allo-HSCT recipients, with a 63% mortality at 90 days.
- Higher SOFA scores, fungal infections, and neutropenia independently predict poorer 90-day survival after septic shock.
- Early aminoglycoside therapy correlates with improved short-term survival, though its causal role remains uncertain.
- Age, graft-versus-host disease type, and early bacterial documentation do not independently affect 90-day mortality.
Study Background and Disease Burden
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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.