Family Medicine & Nutrition
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Divergence of Gut Microbiota Mediated by Milk-Derived Small Extracellular Vesicles: Genomic Variation and Metabolic Modulation in Sugars, Amino Acids, and Purines
Milk small extracellular vesicles select genomic variants in gut bacteria, altering sugar, amino acid, and purine metabolism, impacting microbiota differentiation and host neurodevelopmental outcomes.
The Cliff of Aging: Why Your Body Suddenly Feels Old at 30, 45, and 60
New studies reveal that human aging is non-linear, with key biological shifts at 30, 45–55, and 60 years driving accelerated decline in endocrine function and tissue health.
Long-term Ambient Air Pollution Exposure and Asthma Exacerbation Risk in Women: Evidence from the Nurses’ Health Study II
Long-term exposure to ambient air pollutants, notably nitrogen dioxide, is linked to increased asthma exacerbations in women, independent of plant-based diet adherence, underscoring the need for stricter air quality standards and targeted r
Structured Exercise after Adjuvant Chemotherapy for Colon Cancer: Impact on Survival Outcomes
A 3-year structured exercise program post-adjuvant chemotherapy significantly improves disease-free and overall survival in colon cancer patients, based on the CHALLENGE phase 3 RCT involving 889 patients.
Clinical Applications and Drug Interactions of Carotene
This review synthesizes current evidence on carotene’s clinical applications, including vitamin A deficiency treatment, cognitive effects, and bioavailability enhancement, alongside its pharmacological interactions and safety concerns.
Research Advances on Hypericum perforatum (St. John’s Wort): Phytochemistry, Pharmacology, Clinical Applications, and Drug Interactions
Comprehensive review of Hypericum perforatum covering its major chemical constituents, pharmacological effects, clinical uses in depression and pain, and important drug interactions, based on recent PubMed-indexed studies.
Clinical Applications and Synergistic Potential of Garlic and Allicin in Disease Management: A Comprehensive Review
This review consolidates clinical evidence on garlic and allicin’s therapeutic roles across various diseases, their synergistic effects with other supplements, and translational insights into their mechanisms and future applications.
Clinical Advances and Future Research Trends in Ginseng Applications: A Comprehensive Review
This review summarizes the clinical progress of ginseng across neurological, cardiovascular, metabolic, ischemic, and inflammatory disorders, highlighting mechanistic insights and advanced delivery systems, with a forward look at precision
Clinical Therapeutic Value of Curcumin Supplementation in Cardiovascular Disease, Diabetes, Cognitive Function, Aging, and Neurodegenerative Disorders: A Synthesis of Recent Evidence
Current evidence supports curcumin supplementation for reducing cardiovascular risk factors and preventing type 2 diabetes progression, with emerging potential in cognitive decline and aging-related degenerative diseases.
Protective Effects of High-Intensity Interval Training on Cardiovascular, Neurological, and Metabolic Health: An Evidence-Based Review
This review synthesizes recent evidence demonstrating that high-intensity interval training (HIIT) confers cardiometabolic benefits, modulates microvascular and neural function, enhances insulin sensitivity, and improves mental health outco
Hypervitaminosis B12 and Mortality Risk: Unraveling the Controversy Through a Global Systematic Review and Meta-Analysis
A comprehensive meta-analysis reveals that elevated serum vitamin B12 levels do not conclusively predict increased all-cause mortality risk in adults, highlighting the complexity and heterogeneity of existing research.
Anti-Inflammatory Dietary Education Reduces Frailty in Colorectal Cancer Patients: Insights from a 12-Week Randomized Controlled Trial
A 12-week anti-inflammatory dietary education significantly improved frailty, nutritional status, inflammatory biomarkers, and quality of life in frail colorectal cancer patients undergoing chemotherapy.
Synergistic Impact of Probiotic and Omega-3 Supplementation Combined with Ultra-Short Race Pace Training on Sprint Swimming Performance
Combining probiotics and omega-3 supplementation with ultra-short race pace training significantly enhances sprint swimming performance by improving anaerobic capacity, neuromuscular function, and body composition in competitive male swimme
Comparative Impact of 4:3 Intermittent Fasting Versus Daily Caloric Restriction on Eating Behaviors and Appetite Hormones Over 12 Months
A 12-month trial reveals 4:3 intermittent fasting improves binge and uncontrolled eating behaviors more than daily caloric restriction, correlating with greater weight loss, while appetite hormone changes do not differ significantly between
Rhodiola Rosea Supplementation: Evaluating Effects on Strength Performance and Mental Fatigue in Resistance-Trained Adults
This randomized, triple-blinded crossover trial assessed Rhodiola Rosea’s impact on strength performance and cognitive function under mental fatigue; results show minor physical performance benefits but limited effects on mental fatigue or
Recent Advances in High-Intensity Interval Training: Cardiovascular, Metabolic, Diabetes, and Neuroprotective Effects
This review synthesizes recent evidence on the benefits of high-intensity interval training (HIIT) on cardiovascular health, diabetes management, metabolic function, and neuroprotection, highlighting mechanistic insights and clinical implic
Ashwagandha in Clinical Medicine: Evidence Synthesis, Mechanisms, and Therapeutic Potential
This review synthesizes clinical and mechanistic evidence on Ashwagandha, highlighting its adaptogenic, neuropsychiatric, metabolic, and immunomodulatory effects, with insights from RCTs and meta-analyses.
Understanding Ashwagandha
An informative overview of the health benefits and side effects of South African wormwood, also known as Indian ginseng, highlighting its active compounds and effects on human health.
Health Benefits of Valerian, the Natural Sleep Aid
Explore the health benefits of Valerian root, a natural remedy known for promoting sleep, alleviating anxiety, and providing various therapeutic effects.
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