Diabetes & Endocrinology
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Exploring Auricular Acupressure: A Promising Complementary Intervention for Older Adults with Type 2 Diabetes
A recent study investigates auricular acupressure’s effects on glycemic markers, stress, and sleep quality in older adults with Type 2 diabetes, revealing promising outcomes and potential for nursing interventions.
Diabetic Peripheral Neuropathy as a Predictor of Lacunar Stroke in Diabetes Patients
A study reveals diabetic peripheral neuropathy (DPN) significantly associates with cerebral small-vessel disease (SVD), indicating a predictive role for lacunar stroke in diabetic patients and highlighting opportunities for early interventi
Optimal Exercise Order for Glycemic Control in Postmenopausal Women with Type 2 Diabetes
This article reviews a study examining the effects of aerobic versus resistance exercise execution order on glycemia, blood pressure, and heart rate variability in postmenopausal women with type 2 diabetes, emphasizing clinical implications
Optimizing Exercise for Health: The Impact of Aerobic and Resistance Training Order in Postmenopausal Women with Type 2 Diabetes
This study explores the effects of different exercise orders on glycemia, blood pressure, and heart rate variability in postmenopausal women with type 2 diabetes, highlighting some insights for clinical practice.
Predicting Long-Term Mortality: Insights from a Multi-Metabolite Signature in the PREDIMED Trial
A study identified a robust plasma multi-metabolite signature that predicts long-term all-cause mortality in participants from the PREDIMED trial and several US cohorts, providing new insights into metabolic biomarkers.
Sustained Metabolic Benefits of a Remote Ketogenic Nutrition Program in Veterans with Type 2 Diabetes: A 3-Year Observational Study
A 3-year observational study demonstrates that a remotely delivered ketogenic nutrition program leads to sustained improvements in glycemic control, weight, medication use, and metabolic markers among US veterans with type 2 diabetes.
Impact of Dapagliflozin on Cognitive Function in Older Adults with Type 2 Diabetes and Mild Cognitive Impairment
A 36-week study shows that dapagliflozin significantly improves cognitive function and metabolic parameters in middle-aged and older patients with type 2 diabetes and mild cognitive impairment.
Evaluating the Heart Failure Risk in Type 2 Diabetes: Insights from 1.6 Million People in England
This study evaluates the risk of ischaemic and non-ischaemic heart failure in over 1.6 million individuals with type 2 diabetes, highlighting critical insights for prevention strategies.
Multifunctional Dietary Approach to Reduce Intestinal Inflammation in Cardiometabolic Risk Subjects: Insights from the SINFONI Project
This article explores how a multifunctional dietary strategy can alleviate intestinal inflammation linked to cardiometabolic risk by modifying gut microbiota composition.
Anaerobutyricum soehngenii: A New Hope for Glycemic Control
Anaerobutyricum soehngenii supplementation shows promise in improving glycemic control and cardiovascular health in at-risk adults.
Insulin Resistance and Serum Thyroxine as Key Factors in Differentiated Thyroid Carcinoma and Malignant Cytology
This study reveals that increased serum free thyroxine and insulin resistance-associated factors are linked to higher malignancy risk in thyroid nodules, suggesting a complex interplay between metabolic and hormonal factors in thyroid cance
How Birth Control Pills and Smoking Reshape Steroid Hormones
A large study shows oral contraceptives and smoking substantially alter steroid hormone profiles in healthy adults, with implications for disease risk, diagnostics, and treatment decisions.
Simvastatin Added to Escitalopram in Obese Patients With Major Depression: A Rigorous RCT Shows No Antidepressant Benefit Despite Improved Cardiometabolic Markers
A multicenter double-blind RCT (n=160) found that 12 weeks of simvastatin (40 mg) added to escitalopram did not improve depressive symptoms versus placebo, although LDL, total cholesterol, and CRP were reduced.
Once-Weekly Insulin Efsitora: A Paradigm Shift in Initiation of Basal Insulin for Type 2 Diabetes
Weekly fixed-dose insulin efsitora demonstrated noninferiority to daily glargine in reducing HbA1c in insulin-naïve type 2 diabetes, with fewer hypoglycemic events and simpler dose adjustment.
Dual Renal Protection: Finerenone Plus Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes
Combining finerenone with empagliflozin provides superior reduction in albuminuria for patients with chronic kidney disease and type 2 diabetes, without increased adverse events.
Anthocyanin + Prebiotic Fiber for Type 2 Diabetes: A 60‑Day Randomised Trial Shows Improved Glucose and LDL
A double‑blind RCT of 60 patients with T2DM found a 60‑day supplement of riceberry anthocyanin plus inulin and rice bran reduced fasting glucose, HbA1c, and LDL‑C versus placebo with high adherence and no safety signals.
Divergent Metabolic Impacts of Ketogenic Versus Free-Sugar-Restricted Diets: Insights from a 12-Week Randomized Controlled Trial
A 12-week RCT reveals that ketogenic, but not free-sugar-restricted, diets significantly alter glucose tolerance, lipid metabolism, skeletal muscle phenotype, and gut microbiome in healthy adults, despite similar fat mass reductions.
Three Weeks of Ketogenic Diet Significantly Boosts Skeletal Muscle Insulin Sensitivity in Obesity: Insights from a Randomized Crossover Trial
A 3-week ketogenic diet improved skeletal muscle insulin sensitivity and promoted weight loss in individuals with obesity, without significant effects on liver or adipose tissue insulin sensitivity.
Unraveling the Gut-Brain Axis: Microbiota and Metabolite Shifts Predict Seizure Reduction in Children on the Ketogenic Diet
Serum metabolome and gut microbiota changes during ketogenic diet therapy correlate with seizure reduction in drug-resistant pediatric epilepsy, implicating plasmalogens and specific gut microbes in anti-seizure effects.
Effect of a Ketogenic Diet, Time-Restricted Eating, or Alternate-Day Fasting on Weight Loss in Adults with Obesity: A Randomized Clinical Trial
This clinical trial compares the weight loss effects of ketogenic diet, time-restricted eating, and alternate-day fasting against a Mediterranean diet in adults with obesity over three months.
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