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CardiologyActin dynamicsCardiac Arrhythmia

WNT5a Signaling Disruption Drives Cardiac Pathogenesis in LMNA-Related Emery-Dreifuss Muscular Dystrophy

By MedXY|Jun 10, 2026

Aberrant WNT5a-mediated actin filament dynamics underlie cardiac dysfunction and arrhythmias in LMNA-related Emery-Dreifuss Muscular Dystrophy, revealing novel therapeutic targets via RhoA activation and actin stabilization.

Breakthrough Study Reveals WNT5a-Driven Actin Dysregulation as Core Mechanism in LMNA-Related Cardiac Disease

CardiologyCardiac ArrhythmiaEmery-Dreifuss Muscular Dystrophy

WNT5a

Latest news

WNT5a Signaling Disruption Drives Cardiac Pathogenesis in LMNA-Related Emery-Dreifuss Muscular Dystrophy

Breakthrough Study Reveals WNT5a-Driven Actin Dysregulation as Core Mechanism in LMNA-Related Cardiac Disease