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Shortening Sofosbuvir-Velpatasvir Therapy for Non-Cirrhotic Chronic Hepatitis C: Evidence from the RESOLVE Trial in India
GastroenterologySofosbuvir-VelpatasvirHepatitis C

Shortening Sofosbuvir-Velpatasvir Therapy for Non-Cirrhotic Chronic Hepatitis C: Evidence from the RESOLVE Trial in India

By MedXY|Oct 21, 2026

The RESOLVE trial demonstrates that 8 weeks of sofosbuvir-velpatasvir treatment is non-inferior to the standard 12-week regimen in treatment-naive, non-cirrhotic chronic hepatitis C patients, supporting shorter treatment duration without co

Balancing Benefit and Harm: How Long Should Androgen Deprivation Therapy Be Given With Radiotherapy for Localized Prostate Cancer?
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Balancing Benefit and Harm: How Long Should Androgen Deprivation Therapy Be Given With Radiotherapy for Localized Prostate Cancer?

By MedXY|Nov 23, 2025

An individual-patient data meta-analysis of 10,266 men shows nonlinear oncologic benefit from longer ADT with radiotherapy (diminishing beyond 9–12 months) but increasing other-cause mortality with long-term ADT; optimal duration should be

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