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From Mild-to-Moderate to Severe Asthma: Risk Factors and Patient Profiles from the NORDSTAR Cohort and Advances in Severe Asthma Management
Clinical Updatesasthma progressionbiologics

From Mild-to-Moderate to Severe Asthma: Risk Factors and Patient Profiles from the NORDSTAR Cohort and Advances in Severe Asthma Management

By MedXY|Sep 17, 2026

This review summarizes the progression risk from mild-to-moderate to severe asthma based on the NORDSTAR cohort and integrates emerging evidence on biologic therapies that improve severe asthma outcomes across diverse patient profiles.

Ketoacidosis Risk with SGLT2 Inhibitors in Type 2 Diabetes: Insights from a Scandinavian Cohort Study
Diabetes & Endocrinologytype 2 diabetes
ketoacidosis

Ketoacidosis Risk with SGLT2 Inhibitors in Type 2 Diabetes: Insights from a Scandinavian Cohort Study

By MedXY|Sep 5, 2026

A large Scandinavian study reveals that ketoacidosis risk during SGLT2 inhibitor therapy in type 2 diabetes varies by patient factors and persists beyond early treatment, highlighting the need for ongoing risk assessment and management stra

Long-Term Incidence and Risk Factors for Glaucoma: Insights from the Gangnam Eye Cohort Study
newscohort studyglaucoma

Long-Term Incidence and Risk Factors for Glaucoma: Insights from the Gangnam Eye Cohort Study

By MedXY|Aug 31, 2026

A 10-year Korean cohort study reveals that retinal arteriosclerosis, intraocular pressure, age, serum uric acid, and cholesterol levels significantly increase the risk of structural glaucoma conversion.

Early Childhood Exposure to Crohn’s Disease-Affected Siblings: Implications for Gut Microbiome and Disease Susceptibility
GastroenterologyCrohn’s diseaseSibling exposure

Early Childhood Exposure to Crohn’s Disease-Affected Siblings: Implications for Gut Microbiome and Disease Susceptibility

By MedXY|Aug 28, 2026

Childhood exposure to siblings with Crohn’s disease significantly raises disease risk, linked to distinct gut microbiome changes that may drive disease onset through immune modulation.

Unraveling Attenuated Risk Factor Associations in Secondary Coronary Prevention: Implications for Clinical Practice
Cardiologyindex event biascardiovascular risk prediction

Unraveling Attenuated Risk Factor Associations in Secondary Coronary Prevention: Implications for Clinical Practice

By MedXY|Aug 24, 2026

This study reveals that risk factor associations for subsequent coronary heart disease (CHD) events are systematically attenuated due to index event bias, challenging their clinical interpretation in secondary prevention and emphasizing the

Incidence, Outcomes, and Risk Factors for Mortality in Patients With Sepsis in South Korea: Insights From a Nationwide Cohort Study and Related Evidence
Clinical Updatesepidemiologysepsis

Incidence, Outcomes, and Risk Factors for Mortality in Patients With Sepsis in South Korea: Insights From a Nationwide Cohort Study and Related Evidence

By MedXY|Aug 17, 2026

This review synthesizes nationwide epidemiological trends of sepsis in South Korea from 2011 to 2022, elucidating incidence increases, declining in-hospital mortality, and key clinical and socioeconomic mortality determinants alongside rele

Increased Risk of Dry Eye Disease in Patients with Chronic Pain Conditions: Insights from a Large Retrospective Cohort Study
newschronic paindry eye disease

Increased Risk of Dry Eye Disease in Patients with Chronic Pain Conditions: Insights from a Large Retrospective Cohort Study

By MedXY|Jul 20, 2026

Chronic pain conditions significantly elevate the risk of developing dry eye disease, including cases requiring prescription therapy, emphasizing the need for integrated clinical assessment and management.

Unveiling Posttraumatic Stress Trajectories Following Vaginal Delivery: Implications for Early Identification and Intervention
OB/GYN & Women's Healthchildbirth traumapostpartum PTSD

Unveiling Posttraumatic Stress Trajectories Following Vaginal Delivery: Implications for Early Identification and Intervention

By MedXY|Aug 18, 2026

This multicenter prospective study identifies distinct posttraumatic stress symptom trajectories after vaginal delivery and highlights associated risk factors, providing insights to enhance postpartum PTSD screening and prevention strategie

Cancer Statistics in China: Current Landscape, Risk Factors, and Preventive Strategies
newscancer epidemiologycancer prevention

Cancer Statistics in China: Current Landscape, Risk Factors, and Preventive Strategies

By MedXY|Jan 14, 2026

This article reviews the epidemiological transition of cancer in China, highlighting incidence, mortality, survival trends, major modifiable risk factors, and national prevention and control efforts.

Lower-than-Expected Hemorrhage Risk From Unruptured Brain AVMs: MARS Clarifies Natural History and Key Predictors
Neurologybrain arteriovenous malformationIntracranial Hemorrhage

Lower-than-Expected Hemorrhage Risk From Unruptured Brain AVMs: MARS Clarifies Natural History and Key Predictors

By MedXY|Dec 12, 2025

The MARS multicenter cohort (n=3030) found a lower annual intracranial hemorrhage risk (1.40%/yr) for unruptured brain AVMs than commonly cited. Older age, associated arterial aneurysms, and cerebellar/deep supratentorial location increased

New Persistent Opioid Use Among ICU Survivors After Discharge: Incidence, Predictors, and Nationwide Cohort Insights
AnesthesiologyOpioid Userisk factors

New Persistent Opioid Use Among ICU Survivors After Discharge: Incidence, Predictors, and Nationwide Cohort Insights

By MedXY|Nov 6, 2025

New persistent opioid use develops in 4.2% of opioid-naïve ICU survivors by six months post-discharge, with early opioid prescription as the strongest predictor. Risk varies by opioid potency and patient factors, highlighting tailored taper

Depression, Anxiety and PTSD Associated With Earlier Onset of Alzheimer’s Disease: Psychiatric Burden Lowers Age at Symptom Onset
NeurologyAlzheimer's diseaseEarly-onset dementia

Depression, Anxiety and PTSD Associated With Earlier Onset of Alzheimer’s Disease: Psychiatric Burden Lowers Age at Symptom Onset

By MedXY|Nov 4, 2025

In two large Alzheimer cohorts, a history of depression, anxiety, or PTSD and an increased number of psychiatric comorbidities were associated with earlier age at AD symptom onset by up to ~7–8 years for multi-morbidity.

Targeting Modifiable Risks to Prevent Knee Osteoarthritis
newsepidemiologyknee osteoarthritis

Targeting Modifiable Risks to Prevent Knee Osteoarthritis

By MedXY|Nov 1, 2025

A large systematic review identified prior knee injury, older age, and high bone mineral density as predictors of incident radiographic knee osteoarthritis; overweight/obesity and prior injury explained ~14% of cases—highlighting prevention

Long-Term Progression and Risk Factors of Diabetic Retinopathy in Type 2 Diabetes: Insights from the Skaraborg Cohort in Sweden
Diabetes & Endocrinologycohort studyretinopathy đái tháo đường

Long-Term Progression and Risk Factors of Diabetic Retinopathy in Type 2 Diabetes: Insights from the Skaraborg Cohort in Sweden

By MedXY|Oct 31, 2025

This cohort study tracks diabetic retinopathy incidence over 24 years in type 2 diabetes patients, highlighting the impact of glycemic control and hypertension on disease progression.

Risk Factors and Epidemiological Trends in Severe Pediatric Invasive Group A Streptococcal Disease: Insights from the Netherlands 2015–2024
Critical Careinfectious diseasesPediatrics

Risk Factors and Epidemiological Trends in Severe Pediatric Invasive Group A Streptococcal Disease: Insights from the Netherlands 2015–2024

By MedXY|Oct 27, 2025

A comprehensive study identifies key clinical and temporal risk factors associated with severe invasive group A streptococcal disease in children, highlighting increased severity and incidence post-COVID-19 pandemic in the Netherlands.

Risk Factors Influencing Implant Failure in Full-Arch Fixed Rehabilitation: Insights from a 7-Year Retrospective Study
Dentistryrisk factors

Risk Factors Influencing Implant Failure in Full-Arch Fixed Rehabilitation: Insights from a 7-Year Retrospective Study

By MedXY|Oct 23, 2025

This retrospective study evaluated implant failure rates and identified stage-specific risk factors in fixed full-arch rehabilitations using All-on-4® implants over 1 to 7 years, highlighting bone grafting, implant number, opposing dentitio

Global Health Landscape 1990-2023: Insights from the Global Burden of Disease Study 2023
Public HealthepidemiologyGlobal Burden of Disease

Global Health Landscape 1990-2023: Insights from the Global Burden of Disease Study 2023

By MedXY|Oct 19, 2025

This systematic analysis of the GBD 2023 presents global trends in disease burden, risk factors, and healthy life expectancy across 204 countries, elucidating shifts in NCDs, CMNN diseases, injuries, and underlying risk drivers crucial for

Evaluating Long-Term Outcomes of Contemporary Arthroscopic Bankart Repair in Traumatic Anterior Shoulder Instability: Insights From a 10-Year Follow-Up Study
newslong-term outcomesRecurrence rate

Evaluating Long-Term Outcomes of Contemporary Arthroscopic Bankart Repair in Traumatic Anterior Shoulder Instability: Insights From a 10-Year Follow-Up Study

By MedXY|Oct 10, 2025

This study examines long-term outcomes of a modern arthroscopic Bankart repair technique for traumatic anterior shoulder instability over a minimum 10-year follow-up, highlighting recurrence rates, risk factors, and functional results.

Understanding Oral Cancer: Risks, Symptoms, Treatments, and Prevention
Cardiologyearly detectionprevention

Understanding Oral Cancer: Risks, Symptoms, Treatments, and Prevention

By MedXY|Oct 23, 2025

Explore the causes, warning signs, treatment options, and preventive strategies for oral cancer, a malignant tumor commonly affecting adults aged 40 to 60. Early detection significantly improves survival outcomes.

Venous Thromboembolism in Newly Diagnosed Lymphoma Patients: Insights from a Real-World Vietnamese Cohort
Hematology-OncologyD-dimerLymphoma

Venous Thromboembolism in Newly Diagnosed Lymphoma Patients: Insights from a Real-World Vietnamese Cohort

By MedXY|Oct 5, 2025

An 8.3% incidence of VTE was observed in newly diagnosed lymphoma patients in Vietnam, with pretreatment elevated D-dimer and cardiovascular comorbidities as key risk factors, emphasizing the need for tailored thromboprophylaxis.

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