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De-escalating Axillary Surgery in Early Breast Cancer: Implementing SOUND and INSEMA Trials in Clinical Practice
General SurgerySOUND trialPhẫu thuật Hố nách

De-escalating Axillary Surgery in Early Breast Cancer: Implementing SOUND and INSEMA Trials in Clinical Practice

By MedXY|Oct 17, 2026

Omission of sentinel lymph node biopsy (SLNB) in select postmenopausal patients with early HR+/HER2- breast cancer and negative axillary ultrasound is feasible and safe, reducing surgical morbidity without compromising short-term outcomes.

Clipped Axillary Node Pathology May Support Axillary Surgery De-escalation After Neoadjuvant Therapy in Occult Breast Cancer
General Surgeryclipped node
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Clipped Axillary Node Pathology May Support Axillary Surgery De-escalation After Neoadjuvant Therapy in Occult Breast Cancer

By MedXY|May 18, 2026

In occult breast cancer, clipped-node pathology after neoadjuvant therapy tracked residual axillary disease with high specificity, supporting limited axillary surgery in selected patients, especially those with cN1–cN2 disease.

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