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Evaluating Oral Cephalosporin Generations for Outpatient Pyelonephritis: Insights from the DOGMA-ED Study
Emergency Medicinecephalosporinsemergency medicine

Evaluating Oral Cephalosporin Generations for Outpatient Pyelonephritis: Insights from the DOGMA-ED Study

By MedXY|Oct 13, 2026

A multicenter study shows similar 14-day treatment failure rates among first-, second-, and third-generation oral cephalosporins for outpatient pyelonephritis, supporting flexibility in antibiotic choice post-ED discharge.

Outpatient Versus Inpatient Care for Young Infants with Single Low-Risk PSBI Signs: Insights from a Multicentre Trial in Sub-Saharan Africa and South Asia
Infectious Diseasesoutpatient treatmentPSBI
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Outpatient Versus Inpatient Care for Young Infants with Single Low-Risk PSBI Signs: Insights from a Multicentre Trial in Sub-Saharan Africa and South Asia

By MedXY|Oct 22, 2025

A randomized trial found outpatient treatment of young infants with a single low-mortality-risk sign of possible serious bacterial infection is non-inferior to inpatient care, with lower mortality rates and comparable safety.

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