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MedXY AI/MedXY News/Tag: medullary thyroid carcinoma
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Compartment-Specific Nodal Recurrence in Medullary Thyroid Cancer: Evaluating the Role of Contralateral Prophylactic Central Neck Dissection
newsCentral Neck DissectionRecurrence Patterns

Compartment-Specific Nodal Recurrence in Medullary Thyroid Cancer: Evaluating the Role of Contralateral Prophylactic Central Neck Dissection

By MedXY|Sep 7, 2026

This multicenter study assesses recurrence patterns in medullary thyroid cancer, finding ipsilateral neck sites are the most common recurrence locations, with limited evidence supporting routine contralateral prophylactic central neck disse

Revisiting Level VII Lymph Node Metastasis in Medullary Thyroid Cancer: A Crucial Prognostic Subgroup
Diabetes & Endocrinology
cancer staging
Di căn hạch cổ

Revisiting Level VII Lymph Node Metastasis in Medullary Thyroid Cancer: A Crucial Prognostic Subgroup

By MedXY|Jun 25, 2026

Level VII lymph node metastasis in medullary thyroid cancer signifies a highly aggressive phenotype with the poorest prognosis. Reclassifying level VII nodes as N1b improves prognostic accuracy and could refine staging and treatment strateg

A Novel Approach to Targeting DLL3 with Tarlatamab in a Patient with Medullary Thyroid Carcinoma after Progression on Selpercatinib
newscase reportDLL3

A Novel Approach to Targeting DLL3 with Tarlatamab in a Patient with Medullary Thyroid Carcinoma after Progression on Selpercatinib

By MedXY|Jun 11, 2026

This case report details successful management of RET-altered medullary thyroid carcinoma using tarlatamab after selpercatinib progression, highlighting modified dosing to mitigate toxicities and achieve complete response.

A Novel Approach to Targeting DLL3 with Tarlatamab in a Patient with Medullary Thyroid Carcinoma after Progression on Selpercatinib
Diabetes & Endocrinologybispecific T-cell engagerCytokine release syndrome

A Novel Approach to Targeting DLL3 with Tarlatamab in a Patient with Medullary Thyroid Carcinoma after Progression on Selpercatinib

By MedXY|Jun 10, 2026

A 64-year-old man with RET-altered medullary thyroid carcinoma who progressed on selpercatinib achieved complete response after modified dosing of tarlatamab with manageable CRS/ICANS.

Calcitonin Doubling Rate Sharpens Postoperative Recurrence Risk Stratification in Medullary Thyroid Carcinoma With Biochemical Persistent Disease
Diabetes & Endocrinologybiochemical persistent diseasecalcitonin doubling rate

Calcitonin Doubling Rate Sharpens Postoperative Recurrence Risk Stratification in Medullary Thyroid Carcinoma With Biochemical Persistent Disease

By MedXY|May 4, 2026

In medullary thyroid carcinoma with biochemical persistent disease after surgery, an early postoperative calcitonin doubling rate of at least 0.3/year strongly identified patients at higher recurrence risk and may help tailor surveillance i

Patient-Derived Medullary Thyroid Cancer Models Capture Tumor Plasticity and Drug Resistance Beyond Genomics
newsmedullary thyroid carcinomapatient-derived models

Patient-Derived Medullary Thyroid Cancer Models Capture Tumor Plasticity and Drug Resistance Beyond Genomics

By MedXY|Apr 1, 2026

Patient-derived medullary thyroid cancer models preserved tumor heterogeneity, microenvironmental stem-like features, and variable tyrosine kinase inhibitor response, supporting more personalized preclinical testing.

Surgical Management of Sporadic Medullary Thyroid Cancer: Evidence-Based Comparison of Total Thyroidectomy vs Lobectomy
Clinical UpdatesLobectomymedullary thyroid carcinoma

Surgical Management of Sporadic Medullary Thyroid Cancer: Evidence-Based Comparison of Total Thyroidectomy vs Lobectomy

By MedXY|Mar 2, 2026

This systematic review and meta-analysis suggests that thyroid lobectomy may offer comparable oncologic outcomes to total thyroidectomy for selected patients with sporadic medullary thyroid cancer, while significantly reducing postoperative

Updated Basal Calcitonin Cutoffs Predict Extent of Lymph Node Metastasis in Medullary Thyroid Cancer — Practical Thresholds for Surgery Planning
newsmedullary thyroid carcinoma

Updated Basal Calcitonin Cutoffs Predict Extent of Lymph Node Metastasis in Medullary Thyroid Cancer — Practical Thresholds for Surgery Planning

By MedXY|Nov 23, 2025

A multicenter Chinese cohort of 509 initially treated MTC patients identifies new preoperative basal calcitonin thresholds (241.9, 693.9, 2378.5, 2787.1 pg/mL) that better predict central, ipsilateral lateral, bilateral/contralateral latera

Updated Basal Calcitonin Cutoffs Better Predict Extent of Lymph Node Metastasis in Medullary Thyroid Cancer
Diabetes & Endocrinologymedullary thyroid carcinoma

Updated Basal Calcitonin Cutoffs Better Predict Extent of Lymph Node Metastasis in Medullary Thyroid Cancer

By MedXY|Nov 21, 2025

A multicenter Chinese cohort identifies new preoperative basal calcitonin thresholds (241.9, 693.9, 2378.5, 2787.1 pg/mL) that stratify risk of central, ipsilateral lateral, bilateral/contralateral lateral, and upper mediastinal lymph node

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