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The CLAEG study prospectively evaluated radical surgery in adenocarcinoma of the oesophagogastric junction, demonstrating that prioritizing abdominal lymphadenectomy, neoadjuvant therapy, total gastrectomy, and laparoscopic approaches yield
A prospective cohort study of 30 patients demonstrates that indocyanine green near-infrared fluorescence imaging during minimally invasive esophagectomy achieves 80% sensitivity and 99.4% negative predictive value for detecting malignant ly
A multi-center study reveals that extensive dissection of non-metastatic tumor-draining lymph nodes reduces immunotherapy efficacy in recurrent biliary tract cancer by depleting crucial reservoirs of memory T cells and dendritic cells.
The SENTIX trial shows that sentinel lymph node biopsy without full pelvic lymphadenectomy is safe in early-stage cervical cancer, potentially reducing surgical morbidity without compromising oncologic outcomes.
A large randomized trial finds sentinel lymph-node biopsy alone is noninferior to lymphadenectomy in early cervical cancer, with fewer complications and comparable survival outcomes.