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Unveiling a Novel Fusion circRNA Regulating Mitochondrial Metabolism in t(4;11) B-cell Acute Lymphoblastic Leukemia
Hematology-Oncologyapoptosismitochondrial metabolism

Unveiling a Novel Fusion circRNA Regulating Mitochondrial Metabolism in t(4;11) B-cell Acute Lymphoblastic Leukemia

By MedXY|Aug 24, 2026

A newly identified KMT2A::AFF1-derived fusion circular RNA (AK_7_3) modulates mitochondrial metabolism and apoptosis in t(4;11) B-ALL, revealing potential therapeutic targets for this high-risk leukemia subtype.

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