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12,13-diHOME Levels as a Marker of Brown Adipose Tissue Activation and Outcome in Targeted Temperature Management Post-Cardiac Arrest
Critical Carebrown adipose tissue12

12,13-diHOME Levels as a Marker of Brown Adipose Tissue Activation and Outcome in Targeted Temperature Management Post-Cardiac Arrest

By MedXY|Oct 21, 2026

This study reveals that elevated 12,13-diHOME levels, reflecting brown adipose tissue activation during targeted temperature management after cardiac arrest, correlate with improved survival and distinct immunometabolic profiles.

Therapeutic Hypothermia at 35°C vs. Controlled Normothermia in ICU Heatstroke: Insights from a Pilot RCT
Critical Carechăm sóc hồi sức tích cựcHeatstroke
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Therapeutic Hypothermia at 35°C vs. Controlled Normothermia in ICU Heatstroke: Insights from a Pilot RCT

By MedXY|Sep 3, 2026

A pilot randomized trial comparing targeted temperature management at 35°C versus normothermia in intubated heatstroke patients showed no survival or neurological benefit from hypothermia but increased gastrointestinal injury and arrhythmia

Redefining Post-Cardiac Arrest Care: Two-Year TTM2 Data Confirm No Long-Term Advantage for Targeted Hypothermia
Cardiologycardiac arrestNeurocognition

Redefining Post-Cardiac Arrest Care: Two-Year TTM2 Data Confirm No Long-Term Advantage for Targeted Hypothermia

By MedXY|Feb 20, 2026

This 2-year follow-up of the TTM2 trial demonstrates that targeted hypothermia at 33°C provides no long-term benefit for functional or cognitive recovery compared to targeted normothermia. The findings emphasize the importance of early feve

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