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Integrating Polygenic Risk Scores and Lifestyle Factors to Predict Type 2 Diabetes Onset in the Japanese Population
Diabetes & EndocrinologyJapanese Populationlifestyle factors

Integrating Polygenic Risk Scores and Lifestyle Factors to Predict Type 2 Diabetes Onset in the Japanese Population

By MedXY|Oct 12, 2026

This study demonstrates that polygenic risk scores (PRS) independently predict type 2 diabetes risk in Japanese individuals, and healthy lifestyles can mitigate this risk even among genetically predisposed people, enhancing personalized pre

Long-term Safety of Oral Orforglipron in Japanese Patients with Type 2 Diabetes (ACHIEVE-J): A Multicenter, Randomized, Open-label, Phase 3 Trial
Diabetes & Endocrinology
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GLP-1 receptor agonist
orforglipron

Long-term Safety of Oral Orforglipron in Japanese Patients with Type 2 Diabetes (ACHIEVE-J): A Multicenter, Randomized, Open-label, Phase 3 Trial

By MedXY|Aug 18, 2026

This phase 3 trial evaluates the 52-week safety of oral orforglipron in Japanese adults with type 2 diabetes, showing an acceptable safety profile when used alongside diet, exercise, and oral antihyperglycemic drugs.

Exploring the Link Between the Triglyceride-Glucose Index and Hypertension Incidence in Japanese Adults
Cardiologycardiovascular riskHypertension

Exploring the Link Between the Triglyceride-Glucose Index and Hypertension Incidence in Japanese Adults

By MedXY|Aug 11, 2025

This study highlights the association between the triglyceride-glucose index and the incidence of hypertension in Japanese adults, emphasizing its potential as a predictive marker for cardiovascular health.

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