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Multidimensional Functional Decline Precedes Cardiovascular Events: Insights from the ASPREE Study
CardiologyFrailtycardiovascular disease

Multidimensional Functional Decline Precedes Cardiovascular Events: Insights from the ASPREE Study

By MedXY|Sep 28, 2026

Declines in frailty, intrinsic capacity, and physical quality of life occur years before cardiovascular events, highlighting a prolonged window for early intervention in older adults.

Each Hour Sitting Counts: Sedentary Time Linked to Lower Intrinsic Capacity and Faster Decline in Older Adults
Internal MedicineIntrinsic Capacityolder adults

Each Hour Sitting Counts: Sedentary Time Linked to Lower Intrinsic Capacity and Faster Decline in Older Adults

© 2026 MedXY
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By MedXY|Nov 8, 2025

In a prospective Beijing cohort (BLINDSCE), each additional hour of daily sedentary time was associated with a 1.18-point lower baseline intrinsic capacity and a 0.48-point greater decline over 1 year, suggesting sedentary behavior is a mod

Optimizing Healthy Ageing: The Impact of Physical Activity and Sedentary Behavior on Intrinsic Capacity in Older Adults
Internal MedicineHealthy AgeingIntrinsic Capacity

Optimizing Healthy Ageing: The Impact of Physical Activity and Sedentary Behavior on Intrinsic Capacity in Older Adults

By MedXY|Oct 20, 2025

This prospective Spanish cohort study reveals that moderate-to-vigorous physical activity enhances intrinsic capacity in older adults, while sedentary behavior impairs it, underscoring the role of active lifestyles in promoting healthy agei

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