
Hematology-OncologyAAV-FVIIIfactor VIII
One-stage Assay Reveals Enhanced Thrombin Activation by AAV-Derived Factor VIII: Implications for Hemophilia A Gene Therapy
By MedXY|Oct 9, 2026
This study demonstrates that one-stage assay (OSA) factor VIII activity better reflects the functional enhancement of AAV-derived FVIII in hemophilia A gene therapy, offering superior prediction of bleeding phenotype compared to chromogenic
