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Dynamic Plasma Biomarkers Reveal Multifaceted Effects of Lecanemab in Early Alzheimer’s Disease
Neurologyneurodegenerationamyloid clearance

Dynamic Plasma Biomarkers Reveal Multifaceted Effects of Lecanemab in Early Alzheimer’s Disease

By MedXY|Sep 29, 2026

This longitudinal study investigates plasma biomarker dynamics in Alzheimer’s patients treated with lecanemab, revealing distinct biomarker trajectories that reflect amyloid clearance, tau modulation, and immune responses, offering in

Discriminating Prion Diseases from Alzheimer’s Disease Using Plasma Biomarkers: The Crucial Role of NfL/p-tau217 Ratio
NeurologyAlzheimer's disease
Dấu hiệu sinh học huyết tương

Discriminating Prion Diseases from Alzheimer’s Disease Using Plasma Biomarkers: The Crucial Role of NfL/p-tau217 Ratio

By MedXY|Jul 14, 2026

Plasma phosphorylated tau biomarkers overlap in Alzheimer’s and prion diseases, risking diagnostic confusion. The NfL/p-tau217 ratio emerges as an accurate plasma biomarker to distinguish prion diseases from Alzheimer’s, improving diagnosti

A Two-Marker Plasma Model Closely Mirrors PET-Based Biological Staging of Alzheimer Disease
NeurologyAlzheimer diseaseDấu hiệu sinh học huyết tương

A Two-Marker Plasma Model Closely Mirrors PET-Based Biological Staging of Alzheimer Disease

By MedXY|Jun 7, 2026

Plasma %p-tau217 plus eMTBR-tau243 showed strong agreement with amyloid/tau PET staging, tracked clinical severity, and aligned with neuropathology, supporting a scalable blood-based approach to Alzheimer disease biological staging.

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