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Therapeutic Hypothermia at 35°C vs. Controlled Normothermia in ICU Heatstroke: Insights from a Pilot RCT
Critical Carechăm sóc hồi sức tích cựcHeatstroke

Therapeutic Hypothermia at 35°C vs. Controlled Normothermia in ICU Heatstroke: Insights from a Pilot RCT

By MedXY|Sep 3, 2026

A pilot randomized trial comparing targeted temperature management at 35°C versus normothermia in intubated heatstroke patients showed no survival or neurological benefit from hypothermia but increased gastrointestinal injury and arrhythmia

The Microbiome in Critical Illness: Transforming ICU Care Through Microbial Insights
Critical Carecritical illnessGastrointestinal Microbiota

The Microbiome in Critical Illness: Transforming ICU Care Through Microbial Insights

By MedXY|Aug 27, 2026

This review explores how the human microbiome influences management and outcomes in critically ill patients, emphasizing gastrointestinal microbial dynamics, disruption by critical illness and therapies, and emerging interventions to restor

Post-ICU Frailty in Older Adults Following Septic Shock: Key Predictors and Clinical Implications
Critical Careseptic shockolder adults

Post-ICU Frailty in Older Adults Following Septic Shock: Key Predictors and Clinical Implications

By MedXY|Aug 26, 2026

This study identifies baseline frailty, organ dysfunction severity, and corticosteroid use as independent predictors of severe post-intensive care frailty in older septic shock survivors, highlighting critical factors for targeted post-ICU

Dexmedetomidine Reduces Agitation and Accelerates Recovery in Non-Intubated ICU Patients with Hyperactive Delirium: Insights from the 4D Trial
Anesthesiologyagitationdexmedetomidine

Dexmedetomidine Reduces Agitation and Accelerates Recovery in Non-Intubated ICU Patients with Hyperactive Delirium: Insights from the 4D Trial

By MedXY|Dec 26, 2025

The 4D randomized clinical trial demonstrates that dexmedetomidine significantly reduces agitation duration and improves clinical outcomes in non-intubated ICU patients with hyperactive delirium, providing a safe and effective alternative t

Dexmedetomidine for Analgesia in Nonintubated Patients With Traumatic Rib Fractures: A Randomized Clinical Trial Analysis
Anesthesiologydexmedetomidinechăm sóc hồi sức tích cực

Dexmedetomidine for Analgesia in Nonintubated Patients With Traumatic Rib Fractures: A Randomized Clinical Trial Analysis

By MedXY|Oct 10, 2025

This trial found that adjunctive dexmedetomidine did not reduce opioid use, pain scores, or pulmonary complications in nonintubated ICU patients with traumatic rib fractures, challenging its routine analgesic use in this setting.

Long-Term Outcomes in Critically Ill Adults With Acute Encephalitis: Insights From a Multicenter French Cohort
Neurologyfunctional outcomeschăm sóc hồi sức tích cực

Long-Term Outcomes in Critically Ill Adults With Acute Encephalitis: Insights From a Multicenter French Cohort

By MedXY|Sep 23, 2025

A prospective study of 310 ICU patients with acute encephalitis reveals that half suffer moderate to severe disability or death at 3 months. Autoimmune encephalitis patients show notable recovery over one year, highlighting the need for tai

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