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SleepCARE Trial: CBT-I, Not Bright Light Therapy, Improves Insomnia During Breast Cancer Chemotherapy
Neurologybright light therapyCBT-I

SleepCARE Trial: CBT-I, Not Bright Light Therapy, Improves Insomnia During Breast Cancer Chemotherapy

By MedXY|Oct 4, 2026

In the four-arm SleepCARE trial of 219 women receiving breast cancer chemotherapy, brief CBT-I significantly improved insomnia while bright light therapy did not beat sleep hygiene education. Neither helped fatigue, and combining the two added burden without benefit.

Beyond Monotherapy: Combined High-Intensity Circuit Training and Sleep Health Intervention Synergistically Enhances Sleep and Cardiometabolic Outcomes
newscardiometabolic healthCBT-I

Beyond Monotherapy: Combined High-Intensity Circuit Training and Sleep Health Intervention Synergistically Enhances Sleep and Cardiometabolic Outcomes

By MedXY|Feb 23, 2026

A randomized clinical trial demonstrates that combining high-intensity circuit training (HICT) with sleep health (SH) counseling significantly outperforms mono-interventions in improving sleep efficiency, reducing wakefulness, and enhancing

Low-Dose Amitriptyline vs. CBT-I for Comorbid Insomnia: Statistical Non-Inferiority Meets Clinical Reality
Internal MedicineCBT-Iinsomnia

Low-Dose Amitriptyline vs. CBT-I for Comorbid Insomnia: Statistical Non-Inferiority Meets Clinical Reality

By MedXY|Dec 30, 2025

A multicenter trial finds low-dose amitriptyline non-inferior to CBT-I for comorbid insomnia based on a liberal margin. However, CBT-I yielded superior clinical response rates and fewer side effects, reinforcing its status as the gold-stand

Tai Chi as a Long-term Alternative to CBT-I for Chronic Insomnia in Older Adults: A Randomized Non-inferiority Trial
NeurologyCBT-Iinsomnia

Tai Chi as a Long-term Alternative to CBT-I for Chronic Insomnia in Older Adults: A Randomized Non-inferiority Trial

By MedXY|Dec 30, 2025

A randomized trial comparing Tai Chi and CBT-I in adults over 50 found that while CBT-I offers faster relief, Tai Chi achieves non-inferior results at 12 months post-intervention, suggesting it is a viable long-term strategy for insomnia ma

Scalable Solutions for Sleep: Converging Evidence from a Nationwide RCT and Meta-Analysis Validates Digital CBT-I
NeurologyCBT-Idigital health

Scalable Solutions for Sleep: Converging Evidence from a Nationwide RCT and Meta-Analysis Validates Digital CBT-I

By MedXY|Dec 21, 2025

This article analyzes a nationwide decentralized RCT and a systematic meta-analysis to evaluate the efficacy of digital Cognitive Behavioral Therapy for Insomnia (CBT-I), highlighting its role as a scalable, evidence-based first-line treatm

CBT‑I in Cancer Survivors: Small Subjective Gains, Unclear Objective Benefits — What the 2025 Cochrane Review Tells Clinicians
newscancer careCBT-I

CBT‑I in Cancer Survivors: Small Subjective Gains, Unclear Objective Benefits — What the 2025 Cochrane Review Tells Clinicians

By MedXY|Dec 16, 2025

A 2025 Cochrane review of 21 RCTs (2431 participants) finds cognitive behavioural therapy for insomnia (CBT‑I) yields modest improvements in self‑reported insomnia and sleep quality in people with cancer versus inactive controls or aerobic

Acupuncture for Cancer-Related Insomnia: Limited, Low-Certainty Benefits Compared with Sham or No Treatment; Inferior to CBT‑I
Neurologyacupuncturecancer

Acupuncture for Cancer-Related Insomnia: Limited, Low-Certainty Benefits Compared with Sham or No Treatment; Inferior to CBT‑I

By MedXY|Dec 16, 2025

A 2025 Cochrane review (5 RCTs, 402 patients, mainly women with breast cancer) finds very low- to moderate-certainty evidence that acupuncture delivers small, uncertain sleep diary benefits versus sham or inactive controls and is probably l

Hiệu quả và Độ chấp nhận của Liệu pháp Hành vi Nhận thức cho Chứng mất ngủ trong Bệnh mãn tính: Một Phân tích tổng hợp Toàn diện
newsCBT-I

Hiệu quả và Độ chấp nhận của Liệu pháp Hành vi Nhận thức cho Chứng mất ngủ trong Bệnh mãn tính: Một Phân tích tổng hợp Toàn diện

By MedXY|Sep 28, 2025

Phân tích tổng hợp này xác nhận rằng liệu pháp hành vi nhận thức cho chứng mất ngủ (CBT-I) là một phương pháp điều trị hiệu quả, được chấp nhận tốt, cải thiện kết quả giấc ngủ ở các bệnh mãn tính đa dạng, với tác dụng phụ tối thiểu và tiềm

Efficacy and Acceptability of Cognitive Behavioral Therapy for Insomnia in Chronic Disease: A Comprehensive Meta-Analysis
Clinical UpdatesCBT-Ichronic disease

Efficacy and Acceptability of Cognitive Behavioral Therapy for Insomnia in Chronic Disease: A Comprehensive Meta-Analysis

By MedXY|Sep 28, 2025

This meta-analysis confirms that cognitive behavioral therapy for insomnia (CBT-I) is an effective, well-accepted treatment improving sleep outcomes across diverse chronic diseases, with minimal adverse effects and potential for broad clini

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