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Assessing Cardiovascular Risks Associated with Bruton’s Tyrosine Kinase Inhibitors: Insights from a Meta-Analysis of Phase 3 Trials

By MedXY|Aug 24, 2026

This meta-analysis of 17 Phase 3 RCTs reveals that BTK inhibitors, primarily ibrutinib, increase the risk of non-fatal ischemic cardiovascular events in patients with B-cell malignancies, highlighting important safety considerations.

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