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The SUPREMO randomized trial found that postmastectomy chest‑wall irradiation reduces chest‑wall recurrence but does not improve 10‑year overall survival for intermediate‑risk breast cancer; a large real‑world analysis supports no overall s
A multicentre prospective study shows the ventricular septum curvature ratio on CTPA strongly predicts 30‑day clinical deterioration in normotensive acute pulmonary embolism, outperforming conventional single metrics and offering potential
Interim results from the multicentre phase 3 TRIM trial show no survival benefit from adding scheduled whole‑body CT or FDG‑PET‑CT to physical‑examination follow‑up after radical surgery for stage IIB–C and III cutaneous melanoma at median
In patients with anterior large‑vessel stroke who achieved successful reperfusion, lower penumbral oxygen extraction fraction (OEFr) on baseline DSC‑MRI independently predicted substantial infarct growth and greater penumbra-to-infarct conv
In a large population-based sample, cartilage T2 relaxation times correlated with BMI and were higher in knees with MRI-defined osteoarthritis, particularly in lateral cartilage subregions; T2 did not reflect patient-reported symptoms.
This study reveals reduced brain iron in the substantia nigra-ventral tegmental area correlating with increased striatal dopamine synthesis in schizophrenia, suggesting novel neurobiological mechanisms and potential therapeutic targets.
This study highlights the complementary utility of liver corrected T1 (cT1) and magnetic resonance elastography (MRE) for predicting chronic liver disease progression, emphasizing the critical prognostic role of disease activity beyond fibr
This multinational real-world study reveals limited sensitivity and prognostic value of radiologic extranodal extension (iENE) in HPV-positive oropharyngeal cancer, highlighting the enhanced accuracy with combined CT and MRI and the need fo
An AI-driven model accurately detects imaging-based extranodal extension in HPV-positive oropharyngeal cancer from CT scans, improving outcome prediction beyond expert radiologist assessments and identifying patients at higher risk of poore
This clinical trial prospectively evaluates how a 12-gene expression assay (DCIS score) guides postoperative radiotherapy decisions after breast-conserving surgery in ductal carcinoma in situ, showing tailored radiotherapy use may reduce ip
The PRIME trial demonstrates that biparametric MRI, omitting contrast enhancement, is noninferior to multiparametric MRI in detecting clinically significant prostate cancer, offering a faster, cost-effective alternative potentially transfor
Combining MRI and CT improves detection of nonviable disappearing colorectal liver metastases but does not reliably confirm nonviability, challenging the management of such lesions post-chemotherapy.
Delayed cannabis test results in children under 6 with poisoning symptoms prolong ED visits and influence neuroimaging use. Faster toxicology screening could optimize care and reduce unnecessary scans.
This cohort study reveals that women with screen-detected breast cancer who missed the immediate prior mammography screening have larger tumors, more advanced disease, and worse breast cancer-specific survival, suggesting delayed detection
A phase 2 randomized trial demonstrates that PSMA-PET-guided intensification of salvage radiotherapy after radical prostatectomy significantly improves failure-free survival without added toxicity.
Integrated radiomic-clinical machine learning models outperform traditional clinical biomarkers in predicting survival and treatment response in unresectable hepatocellular carcinoma patients undergoing atezolizumab plus bevacizumab therapy
This article reviews a prospective study evaluating noninvasive anatomical and functional imaging methods to determine hemodynamic significance in right anomalous aortic origin of a coronary artery (R-AAOCA), proposing a stepwise diagnostic
Reduced retinal parafoveal vascular density measured by OCTA independently correlates with subclinical coronary atherosclerosis, revealing a novel noninvasive biomarker for cardiovascular risk assessment beyond traditional factors.
A large cohort study links radiation exposure from pediatric medical imaging to a modest but significant increase in hematologic cancer risk, underlining the need for judicious imaging use in children and adolescents.
A multicenter trial shows cardiac MRI offers comparable sensitivity to invasive coronary angiography for diagnosing ischemic cardiomyopathy, reducing invasive procedures in newly diagnosed heart failure patients.
