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MedXY News/Urology

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Urology

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Clinical Updates

SGLT2 Inhibitors Lower Mortality Risk Post-UTI in Diabetes

Recent research indicates that patients with type 2 diabetes who use SGLT2 inhibitors after a urinary tract infection have a lower mortality risk compared to those using DPP-4 inhibitors.

Aug 13, 2025
Clinical Updates

Teflon (PTFE) Microplastics Impair Sperm Formation

A multi‑institutional Advanced Science study links PTFE microplastic bioaccumulation to impaired spermatogenesis via SKAP2 suppression and shows that SKAP2‑rich milk‑derived extracellular vesicles restore sperm structure and function in hum

Aug 9, 2025Sign in to read
Clinical Updates

Ureteroscopy vs Shockwave Lithotripsy in Children and Adolescents: A Large Multicenter Nonrandomized Trial Challenges Current Practice

In 1,142 patients aged 8–21, a nonrandomized multicenter trial found no clinically meaningful difference in 6-week sonographic stone clearance between ureteroscopy and shockwave lithotripsy; SWL was associated with less pain and fewer misse

Aug 9, 2025
Clinical Updates

KEYNOTE-991: Pembrolizumab Does Not Improve Outcomes in Metastatic Hormone-Sensitive Prostate Cancer—A Phase III Clinical Trial Analysis

KEYNOTE-991 shows pembrolizumab does not improve progression-free or overall survival for mHSPC, and increases serious adverse events when added to enzalutamide and ADT.

Aug 8, 2025Sign in to read
Medical News

Optimizing Male Fertility: The Science Behind Abstinence and Sperm Quality

Discover the optimal abstinence period for male fertility and learn how lifestyle choices impact sperm quality.

Aug 8, 2025
news

Understanding and Improving Ejaculation Control: Strategies for Men’s Sexual Health

Ejaculation control is a common concern for men, impacting confidence and relationships. This article explores causes, solutions, and practical strategies for improvement.

Aug 8, 2025
news

Three Types of Exercise That Can Boost Men’s Sexual Health: The Science Behind Stronger Performance

Discover how aerobic exercise, strength training, and pelvic floor exercises can enhance men’s sexual function, supported by clinical evidence and expert advice.

Aug 8, 2025
news

Unlocking the Benefits of Squats for Male Sexual Health

Explore the scientific principles and practical strategies of using squats to boost male sexual health, supported by research and expert insights.

Aug 8, 2025
Clinical Updates

PARP inhibitors shine: How the TALAPRO-2 trial is changing the landscape of prostate cancer with precision medicine

Treatment for advanced prostate cancer has advanced significantly in the past decade, but metastatic castration-resistant...

Aug 7, 2025
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Clinical Updates

Testosterone Therapy in Middle-Aged and Older Men with Hypogonadism: Balancing Clinical Benefits and Risks

Testosterone therapy offers modest benefits for sexual function, anemia, and bone health in older men with hypogonadism, but increases risks of venous thromboembolism, fractures, and arrhythmias. Careful patient selection and individualized

Aug 6, 2025
news

Symptoms of Pelvic Inflammatory Disease: The Three Most Distinctive Signs

Pelvic inflammatory disease (PID) commonly presents with lower abdominal pain, abnormal vaginal discharge, and systemic symptoms like fever. Early recognition and treatment are vital to prevent complications.

Aug 6, 2025Sign in to read
news

Serenoa repens (Saw Palmetto) in Benign Prostatic Hyperplasia: Clinical Evidence and Implications for Practice

Recent high-quality evidence indicates that Serenoa repens provides little to no benefit for lower urinary tract symptoms due to benign prostatic enlargement compared to placebo.

Aug 6, 2025
news

Can Kidney Stone Sufferers Safely Take Calcium Supplements? Unveiling the Truth

Exploring the relationship between calcium intake and kidney stones, this article provides evidence-based guidance for patients and health professionals.

Aug 6, 2025Sign in to read
Clinical Updates

Enfortumab Vedotin Plus Pembrolizumab vs Chemotherapy in Untreated Locally Advanced or Metastatic Urothelial Cancer: Patient-Reported Outcomes from the EV-302 Phase 3 Study

The EV-302 trial shows enfortumab vedotin plus pembrolizumab improves survival and quality of life over platinum-based chemotherapy in untreated advanced urothelial cancer patients.

Aug 3, 2025Sign in to read
Clinical Updates

Early Toxicity Comparison of Moderately Hypofractionated Radiotherapy and Stereotactic Body Radiotherapy in Prostate Cancer: Insights from the PACE-C Trial

The PACE-C phase 3 trial shows that stereotactic body radiotherapy (SBRT) and moderately hypofractionated radiotherapy (MHRT) have comparable early toxicity profiles in intermediate- and high-risk prostate cancer patients.

Aug 2, 2025
Clinical Updates

Cabozantinib Plus Atezolizumab in mCRPC: CONTACT-02 Phase 3 Final Results and Clinical Implications

The CONTACT-02 phase 3 trial shows cabozantinib plus atezolizumab improves progression-free survival but not overall survival in advanced mCRPC post-ARPI, offering a novel non-androgen receptor-based option.

Aug 2, 2025
Clinical Updates

Individualised Versus Standard 10-Day Antibiotic Therapy in Pediatric Febrile UTI: Insights from the INDI-UTI Trial

A Danish multicentre trial found individualised, shorter antibiotic regimens for febrile pediatric UTIs reduce overall antibiotic exposure and adverse events, but with a modestly higher recurrence risk compared to standard 10-day treatment.

Aug 2, 2025
Clinical Updates

Doxycycline Post-Exposure Prophylaxis Significantly Reduces Bacterial STIs Among MSM and Transgender Women: Final Results from the DoxyPEP Trial

The DoxyPEP trial demonstrates that doxycycline post-exposure prophylaxis markedly lowers bacterial STI incidence in men who have sex with men and transgender women, with good tolerability and minimal resistance over 12 months.

Aug 2, 2025
Clinical Updates

Metformin in Prostate Cancer: Revisiting Hopes and Realities After Recent Phase 3 Trials

Recent large RCTs show metformin does not improve survival or reduce metabolic syndrome risk in prostate cancer patients on ADT, though it modestly improves metabolic parameters.

Aug 2, 2025
Clinical Updates

First-in-Human Results of Terbium-161 PSMA Radioligand Therapy in mCRPC: Insights from the VIOLET Study

A phase 1/2 trial demonstrates the safety of [161Tb]Tb-PSMA-I&T, a novel dual beta-Auger radioligand, in heavily pretreated metastatic castration-resistant prostate cancer patients, supporting further clinical investigation.

Aug 2, 2025
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