Urology
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Early Toxicity Comparison of Moderately Hypofractionated Radiotherapy and Stereotactic Body Radiotherapy in Prostate Cancer: Insights from the PACE-C Trial
The PACE-C phase 3 trial shows that stereotactic body radiotherapy (SBRT) and moderately hypofractionated radiotherapy (MHRT) have comparable early toxicity profiles in intermediate- and high-risk prostate cancer patients.
Cabozantinib Plus Atezolizumab in mCRPC: CONTACT-02 Phase 3 Final Results and Clinical Implications
The CONTACT-02 phase 3 trial shows cabozantinib plus atezolizumab improves progression-free survival but not overall survival in advanced mCRPC post-ARPI, offering a novel non-androgen receptor-based option.
Individualised Versus Standard 10-Day Antibiotic Therapy in Pediatric Febrile UTI: Insights from the INDI-UTI Trial
A Danish multicentre trial found individualised, shorter antibiotic regimens for febrile pediatric UTIs reduce overall antibiotic exposure and adverse events, but with a modestly higher recurrence risk compared to standard 10-day treatment.
Doxycycline Post-Exposure Prophylaxis Significantly Reduces Bacterial STIs Among MSM and Transgender Women: Final Results from the DoxyPEP Trial
The DoxyPEP trial demonstrates that doxycycline post-exposure prophylaxis markedly lowers bacterial STI incidence in men who have sex with men and transgender women, with good tolerability and minimal resistance over 12 months.
Metformin in Prostate Cancer: Revisiting Hopes and Realities After Recent Phase 3 Trials
Recent large RCTs show metformin does not improve survival or reduce metabolic syndrome risk in prostate cancer patients on ADT, though it modestly improves metabolic parameters.
First-in-Human Results of Terbium-161 PSMA Radioligand Therapy in mCRPC: Insights from the VIOLET Study
A phase 1/2 trial demonstrates the safety of [161Tb]Tb-PSMA-I&T, a novel dual beta-Auger radioligand, in heavily pretreated metastatic castration-resistant prostate cancer patients, supporting further clinical investigation.
How to Make Urology Care More Comfortable for Women
Exploring why women often feel discomfort during urology visits and actionable strategies to create a more welcoming, effective clinical experience.
Understanding and Preventing Prostatitis: What Every Man Should Know and Do
Prostatitis is common and often misunderstood. Learn the latest science, dispel myths, and discover practical steps to keep your prostate healthy.
Does More Sex Mean a Longer Life? The Surprising Science Behind Sexual Activity and Longevity
Exploring whether more frequent sex truly leads to a longer life, this article examines scientific evidence, dispels myths, and offers practical sexual wellness advice for couples.
When Sex Ends Without Ejaculation: Understanding Ejaculatory Dysfunction
Persistent inability to ejaculate during sex may indicate ejaculatory dysfunction, a common but often misunderstood men’s health issue. This article explores causes, myths, and practical steps for care.
Treating Chronic Prostatitis: Why Subtyping Matters for Effective Care
Chronic prostatitis is complex and requires tailored treatment based on its specific subtype. Learn why accurate diagnosis is key for better outcomes.
Guarding the ‘Life Gland’: What Every Man Should Know About Prostate Health
Explore the vital role of the prostate, common misconceptions, science-backed practices, and expert insights to safeguard men’s health at every age.
From Boyhood to Manhood: Recognizing and Addressing Pubertal Developmental Disorders
Explore the science, warning signs, and practical advice on abnormal male puberty, bridging knowledge for families and clinicians.
Frequent Urination After Drinking Water vs. Rare Bathroom Breaks: Which Is Healthier?
Does urinating often after drinking water mean better health? This article explores hydration, bladder habits, and what science says about bathroom frequency.
Can Erectile Dysfunction Recover on Its Own? Science, Myths, and Practical Guidance
Explore whether erectile dysfunction can resolve naturally, the science behind recovery, and evidence-based strategies for optimal sexual health.
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