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Recent large-cohort analyses reveal that donor hospital distance from OPO headquarters does not increase deceased donor kidney nonuse, while policy changes like KAS250 temporarily raise nonuse rates but overall kidney utilization continues
An innovative, ultra-low-cost normothermic machine perfusion (NMP) system was developed and validated, enabling extended organ preservation and in vivo function in porcine and human tissues, offering affordable platforms for research and th
Raman spectroscopy-based urine molecular fingerprinting offers a promising non-invasive biomarker to predict delayed graft function, assess baseline kidney allograft quality, and monitor transplant health postoperatively in patients receivi
A new OPTN policy removing race from eGFR calculations shows promise in increasing kidney transplantation access for Black patients by adding waiting time credits, while not disadvantaging others on the waitlist.
A novel nomogram using pretransplant triglycerides and body weight shows promise to guide early mycophenolate mofetil dosing after kidney transplantation, potentially reducing drug overexposure before therapeutic drug monitoring is feasible
Indexing donor kidney parenchymal volume by recipient BMI via routine ultrasound strongly predicts one-year kidney graft function, offering a practical surrogate for graft-recipient size matching.
The Semi-Elective Transplant Initiative (SETI) introduces a systems-based approach to deceased-donor kidney transplantation, improving logistics and graft utilization by shifting to proactive scheduling and expanded machine perfusion, witho
This Swiss retrospective study reveals that while obesity in kidney transplant recipients increases early surgical complications and delayed graft function, it does not affect long-term patient or graft survival, suggesting obesity alone sh
This study elucidates the distinct clinical, pathological, and prognostic differences between native and allograft BK polyomavirus nephropathy, highlighting the severity and poorer outcomes associated with native-kidney BKPyVN and stressing
Following the 2023 US safety net policy for kidney after lung transplantation, a shift from simultaneous lung-kidney transplants to early kidney transplantation post lung transplant was observed, with improved short-term outcomes and reduce
A 7-day perioperative sofosbuvir/velpatasvir prophylaxis in HCV-positive donor to HCV-negative recipient kidney transplants demonstrated sustained virologic response in over 92% of cases, with favorable 1-year graft survival and function.
Sequential use of normothermic regional perfusion and hypothermic machine perfusion in kidney transplants from DCD donors reduces delayed graft function, highlighting enhanced organ preservation strategies.
This study identifies pre-transplant left atrial volume index as a potential predictor for overall one-year morbidity following kidney transplantation, highlighting its clinical relevance beyond traditional cardiac risk markers.
In a nationwide U.S. analysis of 21,010 adult DCD kidney transplants, normothermic regional perfusion lowered delayed graft function, shortened hospital stay, and improved graft and patient survival, with the greatest benefit in higher-risk
Deceased donor kidney transplantation improves survival compared to dialysis waitlisting, with benefits varying by donor kidney quality and recipient age. Low-risk kidneys yield the greatest survival gains, particularly in older recipients.
