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Beyond the Restrictive Paradigm: Redefining Left Ventricular Phenotypes and Prognosis in Cardiac Amyloidosis

MedXY Editorial Team•Mar 2, 2026•Cardiology
echocardiographyheart failureprognosis心脏淀粉样变性

Highlights

At the time of diagnosis, approximately one-third of patients with cardiac amyloidosis (CA) present with preserved left ventricular function, challenging the traditional view that the disease is synonymous with restrictive physiology.

Restrictive ventricular physiology remains the most prevalent phenotype (approximately 56-59%), while systolic dysfunction (LVEF ≤40%) is relatively uncommon at presentation, occurring in only 8-12% of cases.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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