Highlights
– The randomized multicentre OCCUPI trial (n=1604) found OCT guidance during PCI for complex lesions reduced 1‑year major adverse cardiac events (MACE) versus angiography alone (5% vs 7%; HR 0.62; p=0.023).
– An as‑treated OCT subanalysis (n=773 with post‑stent OCT) identified that achievement of predefined OCT optimization criteria (stent expansion, apposition, absence of major edge dissection) occurred in 71% and was associated with markedly lower 1‑year events (2.9% vs 9.4%; HR 0.30).
