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Long-Term Quality of Life Outcomes in Older Patients Undergoing Heart Transplantation or Mechanical Circulatory Support: Insights from the SUSTAIN-IT Study

MedXY Editorial Team•Sep 23, 2026•Cardiology
Heart Transplantationheart failuremechanical circulatory supportquality of life

Highlight

The SUSTAIN-IT study evaluated changes in health-related quality of life (HRQOL) over two years in older adults (60-80 years) with advanced heart failure undergoing heart transplantation (HT) or long-term mechanical circulatory support (MCS). Patients who underwent HT without pretransplant MCS and those with long-term MCS experienced significant and sustained improvements in HRQOL, whereas those with HT and pretransplant MCS showed limited HRQOL gains. Long-term MCS was associated with lower overall HRQOL scores compared to HT without MCS.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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