Long-Term Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement: A Meta-Analysis of Time-to-Event Data

Highlight

• Transcatheter aortic valve implantation (TAVI) shows early superiority over surgical aortic valve replacement (SAVR) in preventing death or stroke, especially in high-risk patients.
• This benefit attenuates over the long term, with no statistically significant difference observed at 5-year follow-up across low, intermediate, and high-risk groups.
• Risk profile strongly influences event rates, with high-risk patients experiencing greater absolute benefits from TAVI over time.

Study Background