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The FAVOR III China trial demonstrates that QFR-guided percutaneous coronary intervention significantly reduces major adverse cardiac events over 5 years, mainly by decreasing myocardial infarction and ischemia-driven revascularization comp
This analysis of a randomized trial finds no survival benefit at 15 years for bilateral versus single internal thoracic artery grafting in coronary bypass surgery, highlighting the need for further trials to clarify the multiple arterial gr
A 25-year synthesis of research on gestational diabetes mellitus revealing early metabolic alterations, prevention strategies, optimized treatments, and lifelong consequences for mothers and offspring.
This study analyzes healthcare usage up to 12 months after COVID-19 infection, revealing prolonged increased utilization—especially among hospitalized patients—highlighting ongoing care needs for survivors.
This study characterizes abnormal lymphatic reflux patterns in primary chylopericardium using direct lymphangiography and demonstrates that guided cervical thoracic duct exploration yields a 66% long-term success rate, with specific reflux
This review synthesizes recent evidence on adult subvalvular aortic stenosis, highlighting long-term clinical outcomes, disease progression, and implications for management and follow-up strategy.
In low-risk severe aortic stenosis patients, both TAVR and SAVR provide sustained health status improvements over seven years, with TAVR offering faster early recovery but similar long-term health outcomes.
Hormone therapy initiated within one year after chemoradiotherapy in young patients with locally advanced cervical cancer is associated with reduced metabolic, skeletal, and cerebrovascular risks, and improved survival without increased onc
A 10-year follow-up of a randomized trial comparing conservative nodule excision with segmental resection for rectal endometriosis reveals comparable long-term functional outcomes, low recurrence rates, and sustained symptomatic relief.
This study compares long-term retreatment rates and short-term complications in women undergoing native tissue hysteropexy versus hysterectomy with apical suspension for pelvic organ prolapse, revealing higher retreatment risk but fewer ear
This 10-year randomized clinical trial reveals that sacrospinous hysteropexy with mesh offers lower failure rates and comparable safety to vaginal hysterectomy in treating uterovaginal prolapse, supporting its use as an effective uterine-pr
A randomized trial showed no significant differences in 6- and 12-month cognitive, physical, and quality of life outcomes between early restrictive and liberal fluid resuscitation in sepsis-induced hypotension.
The Ross procedure in adults demonstrates excellent long-term survival, valve durability, and low reintervention rates, supporting its broader use in selected patients at experienced centers.
This analysis reveals comparable 10-year mortality, valve durability, and hemodynamics between SAPIEN 3 transcatheter and surgical aortic valve replacement in intermediate-risk patients, underscoring TAVR’s durable benefit.
The PARTNER 2A 10-year data show higher mortality and reintervention with balloon-expandable SAPIEN XT TAVR versus surgery in intermediate-risk patients, driven mainly by transthoracic access. Contemporary 10-year SAPIEN 3 data, however, su
A 6-year follow-up of guided internet-based CBT for tinnitus found sustained reductions in tinnitus distress, with smaller persistent gains in mood and sleep, despite substantial attrition and the absence of a long-term control group.
A 6-year follow-up study suggests guided internet-based CBT for tinnitus can produce durable reductions in tinnitus distress, with sustained but smaller benefits for mood, insomnia, and life satisfaction.
A 50-year follow-up of biliopancreatic diversion shows sustained weight loss and diabetes remission, but alarmingly high nutritional complications decades after surgery.
The TaCAS long-term follow-up study reveals that a simple, conversation-based intervention can sustain improvements in physical health and independence for up to six years post-stroke, highlighting the lasting impact of patient-centered mot
A large-scale longitudinal study reveals that ICU survivors aged 60–79 face significantly higher 5-year excess mortality and functional decline compared to the general population, whereas outcomes for nonagenarians converge with their peers