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Decoding the Heart Failure Peptidome: A Cross-Sectional Study Uncovers Novel Biomarkers and Patient Clusters

MedXY Editorial Team•Apr 5, 2026•Cardiology
biomarkersheart failuremass spectrometryNatriuretic Peptidespeptidomerenin-angiotensin system

Highlights

This comprehensive plasma peptidome analysis reveals critical insights into heart failure pathophysiology and patient stratification.

First, the study quantified 21,694 unique peptides in plasma from 486 heart failure patients compared to 98 age-matched controls, identifying 1,924 differentially expressed peptides that distinguish diseased from healthy states.

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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