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In patients with distal and medium vessel occlusion strokes, tenecteplase achieves higher early recanalization rates and reduces early infarct growth compared to alteplase, supporting its preferential use in this clinical setting.
The MAD-MT score integrates clinical and procedural factors to optimize mechanical thrombectomy decisions in distal and medium vessel occlusion strokes, guiding tailored treatment and improving functional outcomes.
The DISTAL trial found no 12-month disability or survival benefit from adding endovascular treatment to best medical therapy in mild-to-moderate medium or distal vessel occlusion stroke.